Therapeutic effects of dried persimmon consumption with diet against Triton X-induced hyperlipidemia in male rats | ||||
| مجلة بحوث التربية النوعية | ||||
| Volume 2025, Issue 92, May 2025, Page 1069-1090 PDF (1.7 MB) | ||||
| Document Type: مقالات علمیة محکمة | ||||
| DOI: 10.21608/mbse.2025.382827.1630 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
فايزه الازلي 1; Afaf Ramadan2; رشا محمد نجيب3; عبد الغني محمود عبد الغني  3
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| 1كليه التربيه النوعيه جامعه المنصوره | ||||
| 2كلية التربيه النوعيه جامعة المنصورة | ||||
| 3کلية التربية النوعية جامعة المنصورة | ||||
| Abstract | ||||
| The present investigation assessed the effect of consuming dried whole persimmon , pulp and peel on blood hyperlipidemia in male rats 36 adult male Sprague Dawley rats weighting (128 ± 5 g) were divided into six groups (6 rats each) : six was acted as negative control group receiving only a standard diet and other rat groups were injected with Triton X 100 (100 mg/kg) plus diet and redivided into (v+) group fed on standard diet and four groups which treated with 4.5 mg/kg atorvastatin drug , treatment group by given (100 mg/kg standard diet) of dried persimmon whole, pulp, and peel for 60 days. Compared with the negative control, Triton X 100 group(+ve) showed that the significantly reduced in weight gain , feed efficiency, HDLc , total protein, globulin, and activities of superoxide dismutase and glutathione peroxidase, while significant elevating in total cholesterol, triglycerides, LDLc, VLDLc, total lipids, phospholipids, AST, ALT, albumin/globulin ratio, and malondialdehyde. However, all groups consumed persimmon exhibited marked improvements in weight gain, feed efficiency, HDLc, total protein, globulin, and antioxidant enzyme activities, increased, whereas serum lipids, liver enzymes, albumin/globulin ratio, and MDA levels declined toward normal, this results were similar to group treated with hyperlipidemic drug. Histopathological examination confirmed biochemical results. The cardiac examinations of all groups that consumed persimmon, pulp, and peel showed significant improvement compared to positive control group. These findings suggest that dried whole persimmon, pulp, and peel may help manage hyperlipidemia and oxidative stress, supporting their inclusion in heart-healthy diets. | ||||
| Keywords | ||||
| Persimmon; Triton x100; Hyperlipidemic rats | ||||
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