Ondansetron versus Pregabalin in Control Emetic Attacks during Surgery with Spinal Anesthesia: Review Article | ||||
| The Egyptian Journal of Hospital Medicine | ||||
| Article 115, Volume 99, Issue 1, April 2025, Page 2173-2178 PDF (283.31 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejhm.2025.430877 | ||||
 View on SCiNiTO | ||||
| Abstract | ||||
| Background: All anesthesiologists find it difficult to control intraoperative nausea and vomiting during spinal anesthesia (SA) procedures, mostly due to its multifactorial nature. During operations, SA is a frequently employed method that provides anesthesia without the hazards of general anesthetic (GA). SA can have certain hazards. Hypotension from a nearly total sympathetic block is the most frequent adverse outcome. Antiemetic medications are used to prevent or treat nausea and vomiting, which makes them not only an unpleasant and disturbing experience during the post-operative phase but also potentially a significant contributing element to the post-operative convalescence. Objective: This study aimed to compare between Ondansetron and Pregabalin for control of emetic attacks during surgery with SA. Methods: A thorough search for material on Ondansetron versus Pregabalin in control of emetic attacks during surgery with SA was done in PubMed, Google Scholar, and Science Direct. Only the most recent or thorough investigation, which ran from December 2000 to May 2024, was taken into account. The writers evaluated relevant literature references as well. Because there are insufficient resources for translation, documents written in languages other than English have been ignored. Papers that were not regarded as significant scientific research included dissertations, oral presentations, conference abstracts, and unpublished manuscripts. Conclusions: The most prevalent empirical application of ondansetron is to alleviate nausea and vomiting. Most often, this medication is used to stop nausea and vomiting after surgery. This 5-hydroxytryptamine receptor 3 antagonist, which inhibits serotonin's action, is a strong anti-emetic. In a variety of groups, pregabalin has been used to treat anxiety disorders, chronic pain, and epileptic patient pain. | ||||
| Keywords | ||||
| Ondansetron; Pregabalin; Emetic attacks; SA | ||||
|
Statistics Article View: 19 PDF Download: 14 |
||||
