A Cohort Study to Evaluate Correlation of Pre-Operative CA-125 and Intra-Operative Stage of Endometriosis
ElSewefy, M., Khairy, H., EL Sayed, H., El Sayed, D. (2025). A Cohort Study to Evaluate Correlation of Pre-Operative CA-125 and Intra-Operative Stage of Endometriosis. EKB Journal Management System, 29(3), 17-23. doi: 10.21608/egyfs.2025.431331
Mohamed Sameh ElSewefy; Hasan Tawfik Khairy; Helmy Motawee EL Sayed; Doaa Hamdy Mohammed El Sayed. "A Cohort Study to Evaluate Correlation of Pre-Operative CA-125 and Intra-Operative Stage of Endometriosis". EKB Journal Management System, 29, 3, 2025, 17-23. doi: 10.21608/egyfs.2025.431331
ElSewefy, M., Khairy, H., EL Sayed, H., El Sayed, D. (2025). 'A Cohort Study to Evaluate Correlation of Pre-Operative CA-125 and Intra-Operative Stage of Endometriosis', EKB Journal Management System, 29(3), pp. 17-23. doi: 10.21608/egyfs.2025.431331
ElSewefy, M., Khairy, H., EL Sayed, H., El Sayed, D. A Cohort Study to Evaluate Correlation of Pre-Operative CA-125 and Intra-Operative Stage of Endometriosis. EKB Journal Management System, 2025; 29(3): 17-23. doi: 10.21608/egyfs.2025.431331

A Cohort Study to Evaluate Correlation of Pre-Operative CA-125 and Intra-Operative Stage of Endometriosis

The Egyptian Journal of Fertility and Sterility
Volume 29, Issue 3 - Serial Number 11106352, May 2025, Page 17-23  XML PDF (276.64 K)
Document Type: Original Article
DOI: 10.21608/egyfs.2025.431331
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Authors
Mohamed Sameh ElSewefy1; Hasan Tawfik Khairy2; Helmy Motawee EL Sayed2; Doaa Hamdy Mohammed El Sayed email 3
1Lecturer of Obstetrics and Gynecology, Faculty of Medicine, Ain Shams University
2Professor of Obstetrics and Gynecology, Faculty of Medicine, Ain Shams University
3Master degree, Resident of Obstetrics and Gynecology Faculty of Medicine, Ain Shams University
Abstract
Background: Endometriosis is an estrogen-dependent gynecologic illness that affects many women's ability to conceive, their physical well-being, and their general quality of life.   
Objectives: To ascertain if the stage of endometriosis af-ter surgery and preoperative CA125 were correlated.    
Methods: Our study was conducted at Obstetrics and Gy-naecology Department, Ain Shams university hospitals and conducted on 60 patients with pelvic pain, endome-triotic cysts, known endometriosis.  
Results: The study involved patients aged 30.58 ± 6.19 years with a mean preoperative CA125 of 57.74 ± 127.09, with 93.3% ovarian, 1.7% ovarian, uterosacral ligament, 1.7% tubal, and 1.7% tubal & Douglas P. Adhesion types included no adhesion, filmy, dense, superficial, deep, and bowel wall infiltration. Stages were 25.0% stage 1, 8.3% stage II, 56.7% stage III, and 10.0% stage IV. Median pre-operative CA125 was 22 in stage 1 and 48.5 in stage 4.
Conclusion: The study found that ovarian lesions were the most common site of lesion in 93.3% of patients, with Stage III being the most common stage in 56.7%. The mean preoperative CA125 was 57.74±127.09, and no significant difference was found between endometriosis stages. 
Keywords
Endometriosis; Intra-Operative Stage; Pre-Op-erative; CA -125
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