Role of Hyaluronic Acid Intrauterine Injection in Asherman’s Syndrome in Women Undergoing Hysteroscopy | ||||
The Egyptian Journal of Fertility and Sterility | ||||
Volume 29, Issue 3 - Serial Number 11106352, May 2025, Page 72-82 PDF (318.15 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/egyfs.2025.431336 | ||||
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Authors | ||||
Amr Hassan El Shalakany1; Nancy Naiem Kaldas ![]() | ||||
1Professor of Obstetrics and Gynecology, Faculty of Medicine, Ain Shams University | ||||
2Master degree, Resident of Obstetrics and Gynecology, Faculty of Medicine, Ain Shams University | ||||
3Assistant Professor of Obstetrics and Gynecology, Faculty of Medicine, Ain Shams University | ||||
Abstract | ||||
Background: Asherman’s syndrome an acquired disorder resulting from pregnancy, childbirth, infection, uterine in-tervention or repair of abnormalities in the uterus (e.g., intrauterine septum, bicornuate uterus or myomectomy). Aim of the Work: Investigating the efficacy of injecting Hyaluronic acid intrauterine in Asherman’s patients using hyster oscopic adhesiolysis. Patients and Methods: This randomized clinical trial was conducted at Early Cancer Detection & Endoscopy Unit maternity hospital Ain Shams University from Janu-ary 2023 till March 2024. Results: The Cases Group showed an increase from 8.3% before treatment to 41.7% after treatment, while the Con-trol Group remained relatively stable at 33.3% both be-fore and after treatment. Similarly, the proportion of par-ticipants experiencing mild symptoms in the Cases Group increased from 33.3% before treatment to 50.0% after treatment, whereas the Control Group remained consis-tent at 33.3%. However, the reduction in amenorrhea in the case group compared to the control group, but an in-significant difference between the two groups. Conclusion: Intrauterine adhesions can result from surgi-cal or hysteroscopic intervention, it can be corrected ef-fectively and safely with the use of hysteroscop to restore menstural pattern and fertility. | ||||
Keywords | ||||
Hyaluronic Acid Intrauterine Injection; Ash-erman’s Syndrome; Hysteroscopy | ||||
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