Active Ingredients of Some Egyptian Plants Species with Anticancer Activity and Its Mode of Action | ||
| Arab Journal of Biotechnology | ||
| Volume 24, Issue 1, June 2025, Pages 18-40 PDF (1.43 M) | ||
| Document Type: Review article | ||
| DOI: 10.21608/arjb.2025.365025.1000 | ||
| Authors | ||
| Emad A Shalaby* ; Ahmed Aboul-Enein; Hany El-Shemy; faten Abou-Elella; Amr Nassrallah | ||
| Biochemistry department, Faculty of Agriculture, Cairo University, Giza, Egypt | ||
| Abstract | ||
| Egyptian desert and natural reserves are enriched areas withvarieties of medicinal plants. Due to specific environmental conditions these plants have been professionally used by An-cient Egyptians against several identified diseases at that time, including dental, gynecological, gastrointestinal, and urinary disorders. Nowadays, Egyptians depends on advanced knowledge of these plants as an alternative medicine. Thus, after accumulative experience Egyptians were able to describe the preparation methods, usage part of the plant and against which disease.. The oldest micinal docment was Among these phytochemicals , the Egyptian environmental condi-tions in the desert areas areinduce successive accumulation of different active secondary me-tabolites such as phenolic, flavonoids, plant acids, terpenoids, alkaloids, glycosides etc.. the Egyptian flora have been extensively tested for their active ingredient, antioxidant and anticancer properties. The structure function relationship have been also evaluated. aAs well as, the mechanisms of actions against human cancer cell lines such as apoptosis, necrosis, cell cycle arrest and reduced angiogenesis. . This review closely summarizes the biological activities of different Egyptian medicinal plants (EMP) as antioxidant and anticancer properties as well as the mechanism of actions of the active ingredients isolated from these plants along with their possible future applications in medicinal field. | ||
| Keywords | ||
| Egyptian plants; Biological activities; Mode of action | ||
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