Hemodialysis Impact on QTc Interval: An Arrhythmia Precursor
Abdelraheem, N., Tawfik, G., Sliem, H., Salem, A., Badr-Aldin, W. (2024). Hemodialysis Impact on QTc Interval: An Arrhythmia Precursor. EKB Journal Management System, 27(7), 1-10. doi: 10.21608/scumj.2024.432623
Nada Abdelraheem; Gamal A. Tawfik; Hamdy Sliem; Ahmed Salah Salem; Wallaa Youssef Badr-Aldin. "Hemodialysis Impact on QTc Interval: An Arrhythmia Precursor". EKB Journal Management System, 27, 7, 2024, 1-10. doi: 10.21608/scumj.2024.432623
Abdelraheem, N., Tawfik, G., Sliem, H., Salem, A., Badr-Aldin, W. (2024). 'Hemodialysis Impact on QTc Interval: An Arrhythmia Precursor', EKB Journal Management System, 27(7), pp. 1-10. doi: 10.21608/scumj.2024.432623
Abdelraheem, N., Tawfik, G., Sliem, H., Salem, A., Badr-Aldin, W. Hemodialysis Impact on QTc Interval: An Arrhythmia Precursor. EKB Journal Management System, 2024; 27(7): 1-10. doi: 10.21608/scumj.2024.432623

Hemodialysis Impact on QTc Interval: An Arrhythmia Precursor

Suez Canal University Medical Journal
Article 1, Volume 27, Issue 7, July 2024, Pages 1-10    PDF (779.14 K)
Document Type: Original Article
DOI: 10.21608/scumj.2024.432623
Authors
Nada Abdelraheem* 1; Gamal A. Tawfik2; Hamdy Sliem3; Ahmed Salah Salem4; Wallaa Youssef Badr-Aldin2
1Department of Internal Medicine, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.
2Internal Medicine Department, Nephrology Unit, Faculty of Medicine, Suez Canal University, Ismailia, Egypt
3Internal Medicine Department, Endocrinology unit, Faculty of Medicine, Suez Canal University, Ismailia, Egypt
4Cardiology Department, Faculty of Medicine, Suez Canal University, Ismailia, Egypt
Abstract
Background: Hemodialysis has been implicated as being a trigger for arrhythmias.  There is an increase in arrhythmia risk following the long inter-dialytic period. This data suggest that applying the same parameters of dialysis without daily electrolytes tests may trigger fatal arrhythmias and could be a modifiable cause of sudden cardiac death. Aim: Early detection of arrhythmia to correct its underlying cause and prevent the occurrence of sudden cardiac death. Subjects and Methods: Observational study that included 60 maintenance hemodialysis (HD) patients to assess the prevalence of QTc prolongation before, during, and after HD in patients who are on maintenance HD in the out/inpatient departments of Suez Canal University. Results: High prevalence of QTc prolongation among the studied population, representing 73.3%. The most common primary disease was glomerulonephritis disease (43.2%) (p=0.006). Moreover, it was found that patients with prolonged QTc was significantly associated with longer HD duration (p=0.020), HD length equal or more than 4 hours (p=0.004), intradialytic hypotension (p=0.029), and non-high flow dialyser (p=0.016). Additionally, patients with prolongation of QTc interval had significant higher pre-dialysis K+ & Na+ levels (p < 0.001, 0.002 respectively). Conclusion: QTc prolongation is common in patients on regular HD. Different factors are associated with occurrence of arrhythmias in HD patients.
Keywords
QTc; Sudden cardiac death; Hemodialysis (HD)
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