The association between blood group types and susceptibility to SARS-COVID-19 infection | ||||
| Microbes and Infectious Diseases | ||||
| Articles in Press, Accepted Manuscript, Available Online from 12 June 2025 | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/mid.2025.372362.2663 | ||||
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| Authors | ||||
Noor Ahmed Jihad   1; Shahad Basil Ismael 2; Yasameen Hassan Jumaa 3
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| 1Department of Microbial Biotechnology, College of Biotechnology, Al-Nahrain University. Baghdad, Iraq | ||||
| 2Department of Molecular and Medical Biotechnology, College of Biotechnology, Al-Nahrain University, Iraq | ||||
| 3Department of Molecular and Medical Biotechnology, College of Biotechnology, Al-Nahrain University, Iraq. | ||||
| Abstract | ||||
| Background: A major global health emergency caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has generated the COVID-19 pandemic. Comprehending variables affecting person's vulnerability to infection is crucial in creating efficacious preventive and therapeutic approaches. The current research goal is to ascertain whether the susceptibility of SARS-Cov-2 in clinical population is associated with ABO groups of blood. Methods: The clinical samples of 1224 coronavirus-2 infected patients who attended the Al-Faluga Hospital and Al-Yarmuk Hospital between May and December 2023 were analyzed. The specimens were grouped as per ABO blood groups. Statistical analysis and variations in the distribution of blood type between patients and controls (288 cases) were recorded. Results: Of the 1224 COVID-19 patients, 636 (52%) had type A+ blood group, 390 had type O+ (32%), 168 had type B+ (14%), and 30 had type AB (2%). Participants of type A+ were significantly more prominent in contrast to controls (52% vs. 39.5%) with a chi-square value of 0.0003, p = 0.005, and an odds ratio (OR) of 1.07 (95% CI: 0.9–1.6). Conclusion: Blood type may contribute to an elevated threat of contracting the new coronavirus-2. | ||||
| Keywords | ||||
| Blood group type; SARS-Cov-2; Acute respiratory syndrome; Coronavirus-2 susceptibility; Epidemiology | ||||
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