Exploring the Diversity, Prevalence and Antibiotic Susceptibility of Pathogenic Bacteria in Patients with Burn Injuries in Basra Province, Iraq | ||
| Bulletin of Pharmaceutical Sciences Assiut University | ||
| Articles in Press, Accepted Manuscript, Available Online from 14 June 2025 | ||
| Document Type: Original Article | ||
| DOI: 10.21608/bfsa.2025.370151.2487 | ||
| Authors | ||
| Alaa M. Alrudainy* ; Ali Aboud Shareef | ||
| Dept. of Biology, College of Education for Pure Sciences, University of Basrah | ||
| Abstract | ||
| Background: Burns represent an important cause of morbidity and mortality, constituting a significant global public health issue. Objective: This investigate aims to study the distribution of bacterial species in burn patients in Basra Province and to elucidate their antibiotic resistance patterns. Methods: 192 samples (56 from blood and 136 from skin) were collected from burn wound patients in Al-Fayhaa Burn Centre in Basra, and were identified by biochemical tests, VITEK was utilized to verify the isolates identification with their resistance patterns. Results: Of the 136 skin specimens collected, 83% exhibited positive growth. Among the 141 bacterial isolates recovered, 77.3% were identified as G -ve bacteria, while 22.7% were designated as G +ve. the most predominant bacteria was P. aeruginosa with rate 58.9%, followed by E. coli at 10.6% and S. aureus at 9.9%. The antibiogram profile for P. aeruginosa indicated a serious resistance to all antibiotics, with the exception of colistin (3.6%). In contrast, all S. aureus isolates showed resistance to cefoxitin, benzylpenicillin, and oxacillin. In blood specimens, positive growth was observed in 28.6%, among the 11 bacterial isolates recovered, 54.5% were identified as G +ve and 45.5% as G -ve bacteria. The dominant G +ve isolate was Staphylococcus haemolyticus, with resistance to most tested antibiotics. Enterobacter cloacae, the highest prevalent G -ve isolate, exhibited resistance to all tested antibiotics except for minocycline (50%) and no resistance to amikacin. Conclusion: P. aeruginosa was the most prevalent causative agent in burn injuries in Basra. All S. aureus were MRSA. | ||
| Keywords | ||
| Antibiotic resistance; Pathogenic bacteria; Skin; Blood; Pseudomonas aeruginosa | ||
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