Effect of Early Sepsis Resuscitation Bundle on Patient’s Initial Outcomes at Emergency Department
Mohamed Elhady, M., Alnagshabandi, E., Zaki Rehbeini, D., Faried Abdelwanees, A., Mehrez Mahmoud Ali, M. (2025). Effect of Early Sepsis Resuscitation Bundle on Patient’s Initial Outcomes at Emergency Department. EKB Journal Management System, 16(3), 1-12. doi: 10.21608/ejhc.2025.433438
Mona Mohamed Elhady; Elham Alnagshabandi; Dalia Zaki Rehbeini; Aida Faried Abdelwanees; Marwa Mehrez Mahmoud Ali. "Effect of Early Sepsis Resuscitation Bundle on Patient’s Initial Outcomes at Emergency Department". EKB Journal Management System, 16, 3, 2025, 1-12. doi: 10.21608/ejhc.2025.433438
Mohamed Elhady, M., Alnagshabandi, E., Zaki Rehbeini, D., Faried Abdelwanees, A., Mehrez Mahmoud Ali, M. (2025). 'Effect of Early Sepsis Resuscitation Bundle on Patient’s Initial Outcomes at Emergency Department', EKB Journal Management System, 16(3), pp. 1-12. doi: 10.21608/ejhc.2025.433438
Mohamed Elhady, M., Alnagshabandi, E., Zaki Rehbeini, D., Faried Abdelwanees, A., Mehrez Mahmoud Ali, M. Effect of Early Sepsis Resuscitation Bundle on Patient’s Initial Outcomes at Emergency Department. EKB Journal Management System, 2025; 16(3): 1-12. doi: 10.21608/ejhc.2025.433438

Effect of Early Sepsis Resuscitation Bundle on Patient’s Initial Outcomes at Emergency Department

Egyptian Journal of Health Care
Volume 16, Issue 3, September 2025, Page 1-12  XML PDF (494.26 K)
Document Type: Original Article
DOI: 10.21608/ejhc.2025.433438
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Authors
Mona Mohamed Elhady1; Elham Alnagshabandi2; Dalia Zaki Rehbeini3; Aida Faried Abdelwanees4; Marwa Mehrez Mahmoud Ali email 4
1Emergency and Critical Care Nursing Department, Faculty of Nursing, Mansoura University, El-Mansoura, Egypt. and Emergency and Critical Care Nursing Department, Faculty of Nursing, King Abdulaziz University, Jedda, Saudi Arabia.
2Medical Surgical Nursing Department, Faculty of Nursing, King Abdulaziz University, Jedda, Saudi Arabia.
3Medical education unit, king Abdulaziz university hospital, Jedda, Saudi Arabia
4Emergency and Critical Care Nursing Department, Faculty of Nursing, Mansoura University, El-Mansoura, Egypt.
Abstract
Background: Sepsis remains one of the leading causes of mortality in emergency care, with delayed recognition and treatment contributing significantly to poor outcomes.Early identification and treatment using standardized protocolscan improve patient outcomes. However, inconsistent adherence to these protocols and limited evidence on their impact in emergency departments highlight the need for further research. Aim: The study aims to explore the effectiveness of early sepsis resuscitation bundles amongpatient’s initial outcomes at emergency department.Study Design: A quasi-experimentalstudy was carried out on 100 adults admitted to the emergency unit atEmergency hospital, El Mansoura, Egypt. Samplewas distributed on two groups; the bundle group and non-bundle group. Sepsis Screening Sheet and Sepsis Management Flow-chartwere used to gather data from research subjects. Results: Significant improvement in patient’s initial outcomes was discovered (p≤0.05) among patients in the bundle received group more than control group as reflected by reduction in overall mortality rate(14%vs.28%, P = 0.021), APACHE score(26.969±9.93 versus 43.541±15.63, P=0.044), QSOFA score(1.960 ± 0.63 vs. 2.68 ± 0.71), mechanical ventilation therapy(14% vs. 28%), length of stay in emergency department group (4.842 ± 2.73versus 1.76 ± 0.823, P = 0.029)and admission to ICU(14%vs. 40%).Conclusion: Nurses play a key role in the early detection of sepsis and the prompt initiation of necessary care, which are essential in reducing patient decline and improving clinical prognosis. Research indicates that applying the sepsis treatment bundle within three hours of a patient's arrival to the emergency department correlates with more favorable early outcomes in those diagnosed with sepsis. Recommendation: Implementing an early sepsis bundle within 3 hours of sepsis recognition at the ED, in addition toperform another researches are forcibly recommended.
Keywords
Sepsis; Sepsis bundle; Early sepsis management; and Sepsis outcomes
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