The Effect of β-Sympathomimetics on Amniotic Fluid Volume in Women with Idiopathic Oligohydramnios | ||||
| Evidence Based Women's Health Journal | ||||
| Volume 15, Issue 15, January 2025, Page 1-6 PDF (403.36 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ebwhj.2024.340432.1393 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Eman Ahmed Ali Elbaz; Mohammed Mohammed Eltotongy; Ashraf Ahmed Ghanem; Hossam M Mansour 
| ||||
| Department of Obstetrics and Gynecology, Faculty of Medicine, Mansoura University | ||||
| Abstract | ||||
| Objectives: To evaluate the role of Isoxsuprine hydrochloride in increasing amniotic fluid volume and consequently improving neonatal outcome and surveillance in case of idiopathic oligohydramnios. Methods: This cross-over randomized controlled study was carried out at Outpatient Clinic and Inpatient Ward at Department of Obstetrics and Gynecology at Mansoura University Hospital (MUH), a major tertiary referal hospital for many governorates in the Delta region in Egypt. The included patients were subdivided into two groups: Group 1: 100 cases of pregnant women with oligohydramnios will receive isoxsuprine hydrochloride orally (20mg three times daily) for two weeks. Group 2: 100 cases of pregnant women with oligohydramniose will receive placebo for two weeks. Then group 1 received placebo for another 2 weeks and group 2 received isoxsuprine hydrochloride (the same dose group 1 received i.e. 20mg three times daily) for another 2 weeks. Results: There are significant elevation in group1 at AFI1 , AFI2 and AFI3 . While there was insignificant difference between the studied groups at AFI4. So there are significant elevation in AFI with isoxsuprine. There was significant difference in NST value before and after intervention in both of group1 and group2 as reactive NST was significantly increased after intervention. Conclusion: Isoxsuprine one of the most important treatment in isolated Oligohydramnios. Using isoxsuprine might be useful drug in treatment of Isolated oligohydramnios in pregnant woman. | ||||
| Keywords | ||||
| AFI; Isoxsuprine; Oligohydramnios; ultrasound | ||||
|
Statistics Article View: 65 PDF Download: 29 |
||||
