Association between Interleukin-32 Gene Olymorphism (rs4786370) and the Susceptibility to Preeclampsia in Egyptian Pregnant Women
Elsaeed, I., Ameen, S., Amer, W., Khashaba, R., Yaseen, S. (2024). Association between Interleukin-32 Gene Olymorphism (rs4786370) and the Susceptibility to Preeclampsia in Egyptian Pregnant Women. EKB Journal Management System, 9(12), 63-67. doi: 10.21608/bjas.2025.345604.1556
Ibrahim Mohamed Elsaeed; Seham Gouda Ameen; Wagdy Megahed Amer; Rana Atef Khashaba; Samar Esam Yaseen. "Association between Interleukin-32 Gene Olymorphism (rs4786370) and the Susceptibility to Preeclampsia in Egyptian Pregnant Women". EKB Journal Management System, 9, 12, 2024, 63-67. doi: 10.21608/bjas.2025.345604.1556
Elsaeed, I., Ameen, S., Amer, W., Khashaba, R., Yaseen, S. (2024). 'Association between Interleukin-32 Gene Olymorphism (rs4786370) and the Susceptibility to Preeclampsia in Egyptian Pregnant Women', EKB Journal Management System, 9(12), pp. 63-67. doi: 10.21608/bjas.2025.345604.1556
Elsaeed, I., Ameen, S., Amer, W., Khashaba, R., Yaseen, S. Association between Interleukin-32 Gene Olymorphism (rs4786370) and the Susceptibility to Preeclampsia in Egyptian Pregnant Women. EKB Journal Management System, 2024; 9(12): 63-67. doi: 10.21608/bjas.2025.345604.1556

Association between Interleukin-32 Gene Olymorphism (rs4786370) and the Susceptibility to Preeclampsia in Egyptian Pregnant Women

Benha Journal of Applied Sciences
Volume 9, Issue 12, December 2024, Pages 63-67    PDF (225.5 K)
Document Type: Original Research Papers
DOI: 10.21608/bjas.2025.345604.1556
Authors
Ibrahim Mohamed Elsaeed1; Seham Gouda Ameen2; Wagdy Megahed Amer3; Rana Atef Khashaba2; Samar Esam Yaseen* 4
1Professor of Clinical and Chemical Pathology Faculty of Medicine, Benha University
2Assistant Professor of Clinical and Chemical Pathology Faculty of Medicine, Benha University
3Assistant Professor of Obstetrics and Gynecology Faculty of Medicine, Benha University
4(MSc. – Benha University, 2019) Assistant Lecturer of Clinical and Chemical Pathology Faculty of Medicine – Benha University
Abstract
Background: Preeclampsia (PE) is an organ dysfunction issue unique to pregnancy that manifests as in hypertension and proteinuria.Due to its participation in several important biological processes, interleukin-32 (IL-32), a proinflammatory cytokine mostly expressed by natural killer (NK) cells, monocytes, epithelial cell lines, and T-cells, has become famous. The purpose of this literature study is to discover if there is a correlation between the Interleukin-32 gene polymorphism (rs4786370) and the risk of preeclampsia in pregnant women from Egypt. In conclusion, pregnant women in Egypt may be able to use the IL-32 rs4786370 gene polymorphism as a marker to estimate their risk of preeclampsia.Preeclampsia (PE) is an organ dysfunction issue unique to pregnancy that manifests as in hypertension and proteinuria.Due to its participation in several important biological processes, interleukin-32 (IL-32), a proinflammatory cytokine mostly expressed by natural killer (NK) cells, monocytes, epithelial cell lines, and T-cells, has become famous. The purpose of this literature study is to discover if there is a correlation between the Interleukin-32 gene polymorphism (rs4786370) and the risk of preeclampsia in pregnant women from Egypt. In conclusion, pregnant women in Egypt may be able to use the IL-32 rs4786370 gene polymorphism as a marker to estimate their risk of preeclampsia.
Keywords
Cardiovascular complications; interleukin-32; preeclampsia; and pregnant women
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