Clinical and two-dimensional radiographic assessment of simvastatin versus mineral trioxide aggregate in pulpotomy of vital immature permanent molars: A12 -month randomized clinical trial. | ||||
| Minia Journal of Medical Research | ||||
| Articles in Press, Accepted Manuscript, Available Online from 23 June 2025 | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/mjmr.2025.393579.1985 | ||||
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| Authors | ||||
Mohamed Aboalftooh Shehata  1; Ahmad Elheeny1; Mina Kamal Yassa2
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| 1Pediatric and Community Dentistry Department, Faculty of Dentistry, Minia University | ||||
| 2Paediatric and Community Dentistry Department, Faculty of Dentistry, Minia University, Minia, Egypt. | ||||
| Abstract | ||||
| This randomized controlled study aimed to evaluate the clinical and radiographic success of Simvastatin gel (SMG) versus mineral trioxide aggregate (MTA) in complete pulpotomy of vital immature permanent molars. Methods: Eligible children in the age group of 6 to 8 years with 80 vital immature permanent molars with deep carious lesions were selected. Teeth were randomly assigned into the SMG and MTA groups (40 immature molar per group). After treatment, clinical and radiographic evaluation over 12 months was performed according to the Core Outcome Set (COS) for Vital Pulp Therapy (VPT). Results: after follow up the Clinical success at 12 months was 90% for SMG and 95% for MTA and the difference wasn’t statistically significant. Radiographic analysis showed that the SMG group had significantly better root elongation. Conclusion: Simvastatin offered comparable clinical and radiographic success to MTA, affirming its potential use in complete pulpotomy of vital immature permanent molars with deep caries. | ||||
| Keywords | ||||
| Keywords: Mineral trioxide aggregate; simvastatin; pulpotomy; immature; Apexogenesis | ||||
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