Insulin resistance and severity of coronary lesions in patients with acute coronary syndrome
Gaballah, S., Ghareeb, H., Elmallawany, M., Abdel Ghaffar, N., Elkhashab, K., Abdelrazik, G. (2025). Insulin resistance and severity of coronary lesions in patients with acute coronary syndrome. EKB Journal Management System, 15(2), 24-32. doi: 10.21608/fumj.2025.330070.1413
Samiha Mohamed Gaballah; Hytham soliman Ghareeb; Mahmoud Mohamed Elmallawany; Noha Abdel Ghaffar; Khalid Ahmed Emam Elkhashab; Gomaa Abdelrazik. "Insulin resistance and severity of coronary lesions in patients with acute coronary syndrome". EKB Journal Management System, 15, 2, 2025, 24-32. doi: 10.21608/fumj.2025.330070.1413
Gaballah, S., Ghareeb, H., Elmallawany, M., Abdel Ghaffar, N., Elkhashab, K., Abdelrazik, G. (2025). 'Insulin resistance and severity of coronary lesions in patients with acute coronary syndrome', EKB Journal Management System, 15(2), pp. 24-32. doi: 10.21608/fumj.2025.330070.1413
Gaballah, S., Ghareeb, H., Elmallawany, M., Abdel Ghaffar, N., Elkhashab, K., Abdelrazik, G. Insulin resistance and severity of coronary lesions in patients with acute coronary syndrome. EKB Journal Management System, 2025; 15(2): 24-32. doi: 10.21608/fumj.2025.330070.1413

Insulin resistance and severity of coronary lesions in patients with acute coronary syndrome

Fayoum University Medical Journal
Volume 15, Issue 2, June 2025, Page 24-32  XML PDF (654.93 K)
Document Type: Full Length research Papers
DOI: 10.21608/fumj.2025.330070.1413
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Authors
Samiha Mohamed Gaballah email 1; Hytham soliman Ghareeb2; Mahmoud Mohamed Elmallawany3; Noha Abdel Ghaffar4; Khalid Ahmed Emam Elkhashab5; Gomaa Abdelrazik6
1Cardiology department ,faculty of medicine, fayoum University, fayoum, Egypt
2Associate professor of cardiology Fayoum University
3Lecturer of cardiology at the Faculty of Medicine, Fayoum University, Fayoum, Egypt
4Assistant professor of Clinical Pathology, Clinical Pathology department, Faculty of Medicine Fayoum University, Fayoum, Egypt.
5cardiology department, the Faculty of Medicine, Fayoum university, Fayoum, Egypt
6Associate Professor of cardiology at the Faculty of Medicine, Fayoum university, Fayoum, Egypt
Abstract
Keywords: Insulin resistance, severity of CAD, Gensini score, ACS
Background: Insulin resistance has been found to be an independent risk factor for atherosclerosis and a higher likelihood of coronary artery disease (CAD) in both those with and without diabetes.
Aim of the study: To assess the relation among insulin resistance (IR) and CAD severity.
Methods: Cross-sectional study included one hundred patients presented with ACS then Coronary angiography was performed at cardiology department in 2022. blood samples for insulin level were done. IR was estimated utilizing the homeostatic model assessment index of IR (HOMA-IR) and TYG index Finally Coronary angiography and severity calculation using Genseni Scoring system
Results: There was no significant variation with p-value <0.05 in Genseni level among HOMA-IR levels & TYG index levels
Conclusion:
Gensini score for CAD severity not the best to correlate with insulin resistance indices and better to use another scoring system for CAD severity
Keywords
Keywords: Insulin resistance; severity of CAD; Gensini
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