Synergistic Effects of Intra-Nasal Low-Level Laser Therapy and Bhramari Pranayama on Sino-nasal Symptoms and Sleep Quality in Chronic Rhinosinusitis: A Randomized Controlled Trial | ||||
The Egyptian Journal of Hospital Medicine | ||||
Article 14, Volume 100, Issue 1, July 2025, Page 2620-2625 PDF (696.89 K) | ||||
DOI: 10.21608/ejhm.2025.436780 | ||||
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Abstract | ||||
Background: Chronic rhinosinusitis (CRS) is a persistent, often debilitating inflammatory disorder of the sinonasal mucosa that not only impairs nasal function but also significantly disrupts sleep quality. Until now, non-pharmacological interventions have remained underexplored. Objective: This study aimed to evaluate the efficacy of intra-nasal low-level laser therapy (LLLT) combined with Bhramari Pranayama breathing exercises on sino-nasal symptoms and sleep quality in CRS patients. Methods: 54patients with chronic rhinosinusitis without nasal polyps (CRSsNP) were randomly allocated into two equal groups (n = 27 each). Group A received intra-nasal LLLT (650 nm, 288J/cm², 3×/week) combined with a daily Bhramari Pranayama breathing exercise regimen for four weeks. Group B practiced the daily Bhramari Pranayama breathing exercise and received sham laser for the same duration. SNOT-22 scores for sino-nasal symptom severity and PSQI scores for sleep quality were assessed both at baseline and post-intervention. Results: After the intervention, group A experienced a greater reduction in SNOT-22 scores compared to group B (29% vs. 9%, p = 0.001). Both groups showed improvement in PSQI scores (group A: 36%, group B: 20%, p = 0.001), with no significant difference between groups post-treatment (p = 0.125). Group A’s intervention resulted in a significant reduction in sinonasal symptoms and a greater improvement in sleep quality compared to breathing exercises alone. Conclusion: This study indicated that intra-nasal LLLT, as a non-invasive and low-risk intervention, may offer additional therapeutic benefits by enhancing patient-reported outcomes in CRS. | ||||
Keywords | ||||
Photobiomodulation; Complementary therapy; Breathing techniques; Quality of life; Upper airway inflammation; Sinonasal rehabilitation; Sleep disturbance | ||||
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