Effect of levosimendan on haemodynamics of mechanically Ventillated patient . | ||
| Minia Journal of Medical Research | ||
| Articles in Press, Accepted Manuscript, Available Online from 02 July 2025 | ||
| Document Type: Original Article | ||
| DOI: 10.21608/mjmr.2025.397260.1997 | ||
| Authors | ||
| Sara Gamal Zaki* 1; nagy sayed ali2; mohamed reda3; Ahmed Sayed Ebraheim4 | ||
| 1of Anesthesiology and intensive care Department, Faculty of Medicine, Minia University, Minia, Egypt | ||
| 2Department of anesthesia and intensive care-faculty of medicine- Minia University - Minia- Egypt | ||
| 3Anesthesiology and intensive care Department, Faculty of Medicine, Minia University, Minia, Egypt | ||
| 4Radiology department,medicine faculty,minia university,minia,egypt | ||
| Abstract | ||
| Background: Levosimendan is an inodilator medication that, given its distinctive pharmacological actions and safety profile, represents an appropriate treatment in cases with heart failure with a decreased ejection fraction in the advanced stage of the illness. Objectives: assessment of levosimendan effect on haemodynamics in the mechanically ventilated patients. Study design: A prospective observational Randomised single blind placebo study Method: This study involved 46 mechanically ventillated patients,the patients were allocated into 2 groups. Group1 levosimendan: 23 patients recived levosimendan ,loading dose and maintance infusion for six hours . Group 2 placebo group :23 patients recived placebo preparation infusion ,hamodynamics were recorded for the six hours of infusion,and comparison was made between 2 groups and within the group to assessment the effect of levosimendan on those patients . Results: no significnt changes occured in haemodynamics in patients recived levosimendan compared to placebo group . Conclusion: levosimendan has no significant effect on haemodynamics of mechnically ventillated patient. | ||
| Keywords | ||
| Levosimendan; Mechanically ventillated patient; Intensive care unit; haemodynamics | ||
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