Effect of levosimendan on haemodynamics of mechanically Ventillated patient . | ||||
Minia Journal of Medical Research | ||||
Articles in Press, Accepted Manuscript, Available Online from 02 July 2025 | ||||
Document Type: Original Article | ||||
DOI: 10.21608/mjmr.2025.397260.1997 | ||||
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Authors | ||||
Sara Gamal Zaki ![]() | ||||
1of Anesthesiology and intensive care Department, Faculty of Medicine, Minia University, Minia, Egypt | ||||
2Department of anesthesia and intensive care-faculty of medicine- Minia University - Minia- Egypt | ||||
3Anesthesiology and intensive care Department, Faculty of Medicine, Minia University, Minia, Egypt | ||||
4Radiology department,medicine faculty,minia university,minia,egypt | ||||
Abstract | ||||
Background: Levosimendan is an inodilator medication that, given its distinctive pharmacological actions and safety profile, represents an appropriate treatment in cases with heart failure with a decreased ejection fraction in the advanced stage of the illness. Objectives: assessment of levosimendan effect on haemodynamics in the mechanically ventilated patients. Study design: A prospective observational Randomised single blind placebo study Method: This study involved 46 mechanically ventillated patients,the patients were allocated into 2 groups. Group1 levosimendan: 23 patients recived levosimendan ,loading dose and maintance infusion for six hours . Group 2 placebo group :23 patients recived placebo preparation infusion ,hamodynamics were recorded for the six hours of infusion,and comparison was made between 2 groups and within the group to assessment the effect of levosimendan on those patients . Results: no significnt changes occured in haemodynamics in patients recived levosimendan compared to placebo group . Conclusion: levosimendan has no significant effect on haemodynamics of mechnically ventillated patient. | ||||
Keywords | ||||
Levosimendan; Mechanically ventillated patient; Intensive care unit; haemodynamics | ||||
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