Antibacterial Effects of Some Medicinal Plants on MDR Bacterial Pathogen Isolates from Different Sources | ||
| International Journal of Theoretical and Applied Research | ||
| Volume 4, Issue 1, June 2025, Pages 699-710 PDF (771.29 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ijtar.2025.375404.1120 | ||
| Authors | ||
| somaya shawki Ahmed* 1; Nagwa Mahmoud sidkey2; Amal Ahmed Ibrahim Mekawey3; Asmaa Sami Mansour4 | ||
| 1MSc researcher in microbiology, Botany and Microbiology Department, Faculty of Science for Girls, Al-Azhar University, Cairo, Egypt | ||
| 2Prof. Of Microbiology &Biotechnology, Faculty of Science, Al-Azhar University (girls branch) | ||
| 3Professor of Microbiology at the Regional Center of Mycology and Biotechnology Al-Azhar University | ||
| 4Associate Professor of Microbiology and Immunology, National Research Center | ||
| Abstract | ||
| Abstract Medicinal plants yield numerous antibacterial compounds. These plants possess therapeutic properties and are commonly employed to treat various ailments. In this study, four different medicinal plants (Zingiber officinale, Syzygium aromaticum, Citrus limon, and Allium sativum), traditionally used in medicine, underwent preliminary screening for antimicrobial potential against five pathogenic microorganisms: S. aureus, Klebsiella pneumoniae, Hafnia alvei, Serratia rubidaea and E. coli, which were isolated from patients from different sources. Multi-drug resistant (MDR) Gram-negative pathogenic microorganisms were selected from isolated sputum and blood samples. The extracts of each plant were prepared and tested for their antibacterial potential and minimum inhibitory concentration (MIC) using the agar well diffusion method. The results indicated that all plant extracts utilized in this study exhibited antibacterial activity against the test pathogens. Syzygium aromaticum demonstrated excellent and broad-spectrum activity compared to the other four plant extracts. The greatest result was obtained with ethyl acetate clove extract (26 mm), followed by ginger (22 mm). This study emphasizes the significance of these plant extracts in controlling certain pathogenic microorganisms. Keywords: Medicinal plants, MIC, MDR, Antimicrobial activity, Cloves (Syzygium aromaticum); Ginger (Zingiber officinale) | ||
| Keywords | ||
| Keywords: Medicinal plants, MDR, Antimicrobial activity, Cloves (Syzygium aromaticum); Ginger (Zingiber officinale) | ||
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