Role of Transthoracic Ultrasound in Predicting Weaning from Mechanical Ventilation in NICU | ||||
| Annals of Neonatology | ||||
| Articles in Press, Accepted Manuscript, Available Online from 04 July 2025 | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/anj.2025.386012.1113 | ||||
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| Authors | ||||
Marwa Ibrahem Abdelrazic1; Reham Mohamed Mokhtar  1; Ahmed Hussein Ahmed2; Abdel-Azeem M. El-Mazary 3
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| 1Pediatrics Department, Faculty of Medicine, Minia University, Egypt | ||||
| 2Pulmonology, Chest Department, Faculty of Medicine, Minia University, Egypt | ||||
| 3NICU, Pediatrics Department, Faculty of Medicine, Minia University, Egypt | ||||
| Abstract | ||||
| Background: Mechanical ventilation is an essential life-support measure in intensive care units (ICUs). However, prolonged mechanical ventilation is associated with multiple complications, and timely weaning is crucial for improving patient outcomes. Traditional weaning predictors have limitations in neonatal populations. Recently, transthoracic ultrasonography has emerged as a non-invasive tool to assess diaphragmatic function and potentially predict weaning success. Nevertheless, studies focusing on its application in neonatal populations remain limited, necessitating further investigation. Aim: to assess the role of Transthoracic Ultrasonography in predicting weaning outcomes in Mechanically Ventilated Neonates in nicu. Methods: This was a prospective cross-sectional study included 40 neonates on MV at NICU during a period from Jan 2024 through Jan 2025. All patients were candidates for weaning and have been given a chance for spontaneous breathing trial (SBT), during which transthoracic US was performed for them. The diaphragm thickening fraction (DTF),ivc diameter ,cardiac contractility, and RSBI were assessed. Results: Neonates who failed weaning had significantly lower diaphragmatic thickness at inspiration (DTI) (1.69±0.07 mm) compared to those who succeeded (1.9±0.10 mm, p<0.001). Diaphragmatic thickness at expiration (DTE) was slightly lower in failed cases (1.46±0.08 mm) than in successful cases (1.49±0.06 mm), but this difference was not statistically significant (p=0.31). Conclusions: Failed cases had lower Lower DTI, DTF, contractility and Smaller IVC diameter | ||||
| Keywords | ||||
| neonates; mechanical ventilation; ultrasound; weaning failure; predictors of weaning | ||||
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