Correlation of Clinical Presentation with Endoscopic and Pathological Findings in Chronic Diarrhea Patients Referred for Colonoscopy in a Tertiary Care Hospital | ||
| ARCADEs of MEDICINE | ||
| Articles in Press, Accepted Manuscript, Available Online from 06 July 2025 | ||
| Document Type: Original Research | ||
| DOI: 10.21608/arcmed.2025.375347.1114 | ||
| Authors | ||
| Mohamed Sabry Emara* 1; Rasha Samir2; Mohamed Alboraie3; Amr Abou-ElMagd4 | ||
| 1Gastroenterology and hepatology department, AFCM, Cairo, Egypt. | ||
| 2Internal Medicine Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt | ||
| 3Gastroenterology and Hepatology Department, Armed Forces College of Medicine, Cairo, Egypt | ||
| 4Department of Gastroenterology and Hepatology, Armed Forces College of Medicine, Cairo, Egypt | ||
| Abstract | ||
| Abstract Background: Chronic diarrhea presents a diagnostic challenge due to its wide range of potential etiologies. Accurate diagnosis requires a comprehensive clinical evaluation, including history, physical examination, and targeted investigations. Materials and Methods: This cross-sectional analysis was carried out at the Gastroenterology and Hepatology Department of Kobbry El Kobba Medical Military Complex from September 2022 to June 2023. A total of 177 individuals with chronic diarrhea who underwent colonoscopy were enrolled. Clinical, demographic, laboratory, endoscopic, and histopathological data were collected and analyzed. Results: Out of 177 patients, 81.4% were male, with a mean age of 47.6 ± 18.3 years. Colonoscopy revealed normal mucosal findings in 54.8% of participants. Histopathological evaluation showed that non-specific colitis/ileitis was the most prevalent diagnosis (40.7%), while adenocarcinoma was the least common (10.7%). Conclusions: Over half of the patients exhibited normal colonoscopic findings, yet 14.1% of these were found to have microscopic colitis on histology. This underscores the diagnostic value of routine mucosal biopsies even in the absence of visible abnormalities. | ||
| Keywords | ||
| Chronic diarrhea; polyp; irritable bowel syndrome; ulcerative colitis; Crohn’s disease | ||
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