Determination of Neutrophil-to-Lymphocyte Ratio, Monocyte-to-Lymhocyte Ratio in FIV Positive and Healthy Cats Associated with SIRS | ||||
| Egyptian Journal of Veterinary Sciences | ||||
| Article 30, Volume 56, Issue 8, August 2025, Page 1979-1988 PDF (978.67 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejvs.2025.380098.2857 | ||||
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| Author | ||||
Kemal Aksoy  
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| University of Muğla Sıtkı Koçman, Faculty of Veterinary Medicine Milas, Department of Internal Medicine, Milas, Muğla, Turkey. | ||||
| Abstract | ||||
| This study aimed to reveal the diagnostic role of inflammatory biomarkers of neutrophil-to-lymphocyte ratio (NLR), monocyte-lymphocyte (MLR), and platelet-to-lymphocyte ratio (PLR) in cats infected feline immunodeficiency virus (FIV) and to investigate their usability in determining systemic inflammatory response syndrome (SIRS) in these cats. The study was divided into 2 different groups as FIV-positive and healthy groups. A total of 15 healthy and 15 FIV-positive cats of different breeds and ages were served to the current study. The FIV-positive group was categorised into two subgroups: SIRS positive and SIRS negative. While the median PLR value (p = 0.756) did not significantly differ between the groups, the median NLR (p = 0.049) and MLR (p = 0.019) values of FIV (+) cats were significantly higher than those of the healthy group. The average lymphocyte (p= 0.000) and PLT (p= 0.003) values of the SIRS (+) group were significantly lower compared to the healthy group. When comparing the NLR, MLR, and PLR values of the SIRS (+), SIRS (-), and healthy groups, the SIRS (+) group's median NLR (p=0.012) and MLR (0.030) values were significantly higher than the healthy group's, but the PLR values did not significantly between the three groups (p>0.05). In conclusion, NLR and MLR were significantly higher in FIV (+) cats compared to healthy cats. Furthermore, the significant increase in both parameters among SIRS-positive cats compared to SIRS-negative ones highlights the potential usefulness of MLR in identifying cats at risk for SIRS. | ||||
| Keywords | ||||
| FIV; neutrophil-to-lymphocyte ratio; monocyte-to-lymphocyte ratio; platelet-to-lymphocyte ratio; SIRS | ||||
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