Different Targets in Ablative Surgery in Management of Parkinsonian Disease | ||||
| Al-Azhar International Medical Journal | ||||
| Volume 2024, Issue 4, April 2024 | ||||
| DOI: 10.58675/2682-339X.2366 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Islam Al Aghory; Alaa Ibrahim ; Ahmed Zaki
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| Neurosurgery, Faculty of Medicine for Boys, Al-Azhar University, Cairo, Egypt | ||||
| Abstract | ||||
| Background: Surgical options for Parkinson's disease (PD) consist of ablative procedures and deep brain stimulation (DBS). The targets for ablation are the VIM, the globus pallidus, and the subthalamic nucleus. Aim: To assess efficiency, complications & safety of variable targets in ablative surgery in Parkinsonian disease. Methods: This Retrospective research was conducted on 20 Parkinsonian individuals in 2022. All patients were subjected to the Unified PD Rating Scale (UPDRS), with special attention to the motor score (part III). Results: This study demonstrated improvement in the Unified PD Rating Scale (UPDRS) between preoperative and 6-month postoperative motor symptoms in twenty patients. There were very statistically substantial ( P-value < 0.01), which is highly significant; there was a significant decrease in (UPDRS) from preoperative (40.30 ± 13.48) to 6 months postoperative (12.85± 7.73) as regards Chi-square test and Fisher exact test for comparison of two groups with qualitative data and Independent t-test for comparison between two independent groups with quantitative data and parametric distribution. Conclusions: Ablative surgery can be considered a safe & effective therapy option for PD. | ||||
| Keywords | ||||
| Ablative Surgery; Different Targets; Parkinsonian Disease | ||||
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