Effect of Hyperglycemia on the Outcome of Community-Acquired Pneumonia | ||
| Al-Azhar International Medical Journal | ||
| Volume 2025, Issue 1, January 2025 | ||
| DOI: 10.58675/2682-339X.2876 | ||
| Authors | ||
| Hossam Mohammed1; Marwa Abdelhady2; Aboalnaga Hamed2; Ahmed Nabih2; Hytham Abdalla3 | ||
| 1Chest Diseases, Faculty of Medicine, Luxor University, Luxor, Egypt | ||
| 2Internal Medicine, Faculty of Medicine, Luxor University, Luxor, Egypt | ||
| 3Chest Diseases, Faculty of Medicine, Al-Azhar University, Assiut, Egypt | ||
| Abstract | ||
| Background: Hyperglycemia impairs immune responses, potentially exacerbating community-acquired Pneumonia (CAP) outcomes. Objectives: This work aims to evaluate hyperglycemia's influence on CAP's outcome. Methods: This observational, prospective study investigated 200 elderly CAP individuals (130 nondiabetic, 70 diabetic). Outcomes included ICU admission, mechanical ventilation requirement, oxygen support needs, disease severity (CURB score ≥3), and length of hospital stay. Results: Higher rates of obesity (p=0.003) and significantly older age (p=0.001) were found in diabetic individuals. They exhibited a lower prevalence of sore throat (p=0.001) and fever (p=0.05), with higher neutrophil counts (p=0.004). CT scans revealed more frequent crazy paving patterns in diabetic patients (p=0.01). Diabetic patients had higher rates of ICU admission (p Conclusions: Hyperglycemia in CAP patients was associated with increased disease severity, ICU admission, and mechanical ventilation requirements; it did not significantly impact mortality rates. These findings underscore the importance of glycemic control in managing CAP patients, particularly those with comorbid diabetes. | ||
| Keywords | ||
| Community-acquired pneumonia; hyperglycemia; Elderly; Outcome | ||
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