Hemodynamic Changes Before and After Resuscitation Comparative Study In Septic Shock | ||||
| Al-Azhar International Medical Journal | ||||
| Volume 2025, Issue 3, March 2025, Page 1-6 | ||||
| DOI: 10.58675/2682-339X.2882 | ||||
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| Authors | ||||
| Mohammed Dahashan1; Essam Abdel-Wahab2; Ahmed El-Naggar2 | ||||
| 1Emergency and critical care, Faculty of Medicine for Boys, Al-Azhar University, Cairo, Egypt | ||||
| 2Anesthesia, Intensive Care and Pain Management, Faculty of Medicine for Boys, Al-Azhar University, Cairo, Egypt | ||||
| Abstract | ||||
| Background: Septic shock, a critical condition marked by circulatory failure and organ dysfunction from an abnormal response to infection, requires immediate hemodynamic resuscitation to restore tissue perfusion and improve outcomes. This study assessed changes in hemodynamic parameters in septic shock patients before and after fluid resuscitation. Aim: To evaluate the hemodynamic changes before and after resuscitation by either colloids or crystalloids . Patient and Methods: 60 patients with septic shock in the emergency and critical care departments of Al-Azhar University Hospitals were divided into two groups, A and B, with 30 patients in each group. Hemodynamic parameters such as blood pressure were measured at baseline and three hours after administering 30 mL/kg fluid resuscitation according to standard guidelines. The effects of saline versus albumin were also compared. Results: After fluid resuscitation, significant improvements occurred in systolic blood pressure, mean arterial pressure (65 to 95 mmHg), SvO2 (62% to 72%), and lactate clearance (p Conclusion: Marked hemodynamic improvements occurred following protocolized resuscitation, with crystalloids achieving the best corrections. | ||||
| Keywords | ||||
| Septic shock; Hemodynamics, Resuscitation; Crystalloids; mortality | ||||
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