Prevalence of Vitamin D Deficiency in Late Pregnancy and Its Association with Maternal and Fetal Outcomes | ||||
Al-Azhar International Medical Journal | ||||
Volume 2025, Issue 1, January 2025 | ||||
DOI: 10.58675/2682-339X.2838 | ||||
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Authors | ||||
Mohamed Mohamed1; Abd Elhalim Abd Elhalim1; Ali Hamed2; Abeer Ahmed1 | ||||
1Obstetrics and Gynecology, Faculty of Medicine, Al-Azhar University, Assuit, Egypt | ||||
2Clinical Pathology, Faculty of Medicine, Al-Azhar University, Assuit, Egypt | ||||
Abstract | ||||
Background: Vitamin D is a crucial mineral that significantly influences human metabolic processes, notably maintaining calcium and phosphate balance and regulating bone health. Aim: The purpose of this study is to determine the frequency of vitamin D deficiency in pregnant females during the later stages of pregnancy and to examine its correlation with adverse effects for both the maternal and the fetus. Patients and methods: This was a prospective observational comparative cohort investigation performed on all pregnant females following 36 weeks of gestation attending the outpatient obstetric clinic of Al-Azhar University Hospital (Assuit) -Egypt, starting from January 2023 till August 2023. Results: The mean Apgar score was 8.53±1.73, and the mean baby length was 47.15±1.54. The mean serum level of Vitamin D3 was 55.16±41.3, with 15.6% of patients having Vitamin D3 deficiencies, 15.6% having insufficient levels, 77 having sufficiency, and 15.6% having potential toxicity. An insignificant association has been observed among serum D3 concentrations and pre-eclampsia, IUGR, GDM, and amniotic fluid p>0.05. Nevertheless, there a significant association has been observed between serum D3 levels and preterm birth p= 0.045, and an insignificant association among serum D3 concentrations and postdate p=0.06. Conclusion: The findings of our study indicate a direct correlation between insufficient levels of vitamin D3 in pregnant mothers and negative newborn outcomes, such as low Apgar scores and low birth weight. A significant negative association was seen between blood concentrations of vitamin D3 and preterm birth, as well as prim-section. | ||||
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