Role of Serum Amyloid A Levels in Preeclampsia | ||||
| Al-Azhar International Medical Journal | ||||
| Volume 2023, Issue 1, January 2023 | ||||
| DOI: 10.58675/2682-339X.1887 | ||||
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| Authors | ||||
| Ashraf Hamdy Mohammed; Adel Aly Elboghdady; Abd El-Aty Khairy Abd El-Latif | ||||
| Department of Obstetrics and Gynecology, Faculty of Medicine for boys, Al-Azhar University, Cairo, Egypt | ||||
| Abstract | ||||
| Background: Preeclampsia (PE)is a frequent pregnancy complication and a leading factor in mother and fetal death. The maternal plasma level of SAA may be anticipated to be higher compared to levels seen during a typical pregnancy since preeclampsia is linked to extensive endothelial malfunction, which is thought to be triggered by an enhanced maternal systemic inflammatory response. The maternal plasma level of SAA during a healthy pregnancy may vary from that during a non-pregnancy owing to changes in the inflammatory response, elevated hormone balance, and/or increased adipose tissue. Patients and Methods: At the Department of Obstetrics and Gynecology, Al-Hussein and Sayed Galal Hospitals, Al-Ahar University, and El Dalangat general hospital, 100 women were separated into two groups for this prospective case-control research: (Group I): (Cases group): included50 pregnant preeclamptic women, (Group II): (Control group): included50 pregnant non-preeclamptic women who matched in age, and gestational age with the case group between December 2019 to December 2020. Results: Regarding Serum Amyloid A, there were statistically substantial variations between groups where P Conclusion: Serum amyloid A is a promising biomarker in detect ability and predictability of the pathological development of preeclampsia. Future research studies should be conducted in a multicentric fashion. | ||||
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