Potency of Intravenous Dexamethasone on Preparing the Cervix and Labor Induction | ||||
| Al-Azhar International Medical Journal | ||||
| Volume 2023, Issue 1, January 2023 | ||||
| DOI: 10.58675/2682-339X.2026 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| Madiha Mohamed Hanafy; Hanan Abd El-Monem Mohamed; Hend Atif Mohamed Mesalam Abd Al-Hady | ||||
| Department of Obstetrics and Gynecology, Faculty of Medicine for girls, Al-Azhar University, Cairo, Egypt | ||||
| Abstract | ||||
| Background: Corticosteroids are one strategy for accelerating labor (labor induction). Animal studies show that sheep fetuses and other fetuses secrete cortisol to trigger labor. Extra-amniotic and intravenous (IV) corticosteroids both works. Cortisol and DHEA-S seem to affect the myometrium indirectly via promoting the synthesis of membrane prostaglandins. Elevated levels of estrogen alter the ratio of estrogen to progesterone, which disrupts the fetus' static state and induces myometrium contraction. Aim: This study's objective is to evaluate the effectiveness of intravenous dexamethasone for cervix preparation and labor induction. Subject and Methods: At Al-Zahraa University Hospital and Sayed Galal University Hospital's obstetrics and gynecology departments, the research was conducted. There are 100 patients in the study population. Results: There is no statistically substantial between Steroid and Saline received pregnant females as regard age, GA and type of labor. The duration of 1st of Induction - Active stage and Induction - second Stage was statistically substantial lower in pregnant female who got steroid than those who got saline. Conclusion: Dexamethasone administered intravenously induces the cervix to soften and lowers the period between labor induction and the starting of the active phase of labor by raising the cervix's bishop score. | ||||
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