Vitamin D3 and chronic rhinosinusitis, Is there a relationship?
Basha, S., Hassan, A., Shaaban, M., Younis, M. (2644). Vitamin D3 and chronic rhinosinusitis, Is there a relationship?. EKB Journal Management System, 2023(1), -. doi: 10.58675/2682-339X.1747
Salem Ibrahim Basha; Ahmed Abdelbaset Hassan; Mostafa Mohamed Shaaban; Mohamed Abdelmoneam Younis. "Vitamin D3 and chronic rhinosinusitis, Is there a relationship?". EKB Journal Management System, 2023, 1, 2644, -. doi: 10.58675/2682-339X.1747
Basha, S., Hassan, A., Shaaban, M., Younis, M. (2644). 'Vitamin D3 and chronic rhinosinusitis, Is there a relationship?', EKB Journal Management System, 2023(1), pp. -. doi: 10.58675/2682-339X.1747
Basha, S., Hassan, A., Shaaban, M., Younis, M. Vitamin D3 and chronic rhinosinusitis, Is there a relationship?. EKB Journal Management System, 2644; 2023(1): -. doi: 10.58675/2682-339X.1747

Vitamin D3 and chronic rhinosinusitis, Is there a relationship?

Al-Azhar International Medical Journal
Volume 2023, Issue 1, January 2023  XML
DOI: 10.58675/2682-339X.1747
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Authors
Salem Ibrahim Basha1; Ahmed Abdelbaset Hassan1; Mostafa Mohamed Shaaban2; Mohamed Abdelmoneam Younis1
1Otorhinolaryngology department, Faculty of medicine, Al-Azhar University, Cairo , Egypt.
2Clinical Pathology department, Faculty of medicine, Al-Azhar University, Cairo , Egypt.
Abstract
Background: One of the most prevalent conditions without a proven long-term treatment is chronic rhinosinusitis (CRS). There are two phenotypes of chronic rhinosinusitis (CRS): chronic rhinosinusitis without nasal polyps (CRSsNP) and chronic rhinosinusitis with nasal polyps (CRSwNP). Immunomodulation is thought to be a function of vitamin D (VD), particularly in allergic disorders. Objective: This investigation was done to assess the link between blood VD3 levels and CRS, whether it had polyps or not. Patients and methods: 90 people from both sexes participated in this study. Adults were divided into three categories and given the diagnosis of sinusitis by the American Academy of Otolaryngology Head & Neck Surgery: CRSsNP (30 subjects), CRSwNP (30 subjects), and control group (30 subjects). Using an ELISA (enzyme-linked immunosorbent assay), VD levels were measured (ELISA). Results: The serum 25 (OH) D level varied between the CRSsNP Group (23.10±7.40), CRSwNP Group (22.20±8.12), and Control Group (26.22±8.25). Regarding VD3, there was no discernible difference between the studied groups. Age-related differences across the groups were statistically significant, with CRSwNP being more prevalent in the older age group (55.07±5.78). There was no discernible difference in symptomatology or sex. Conclusions: Chronic rhinosinusitis, whether it had polyps or not, did not correlate with serum vitamin D3 levels. This indicates that low levels of serum 25 (OH) D are not a potential risk factor for CRS in adult patients.
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