Maternal and Fetal Plasma Urocortin Levels in pregnancies Complicated by Preeclampsia | ||||
Al-Azhar International Medical Journal | ||||
Volume 2024, Issue 5, May 2024 | ||||
DOI: 10.58675/2682-339X.2441 | ||||
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Authors | ||||
Farid Hassan1; Mofeed Mohamed1; Mohamed Al-Mohandes2; Nagham Abed El amer3; Hani Mehanna4 | ||||
1Obstetrics and Gynecology, Faculty of Medicine, Al- Azhar University, Cairo, Egypt | ||||
2Obstetrics and Gynecology, El Galaa Maternity Teaching Hospital. Cairo, Egypt | ||||
3Clinical Pathology, El Galaa Maternity Teaching Hospital. Cairo, Egypt | ||||
4Obstetrics and Gynecology, Faculty of Medicine for Boys, Al-Azhar University, Cairo, Egypt | ||||
Abstract | ||||
Background: Preeclampsia is a multisystem illness that manifests in the latter half of pregnancy as end-organ failure, proteinuria, or new-onset hypertension. Aims: seeks to assess urocortin levels in the plasma of the mother and fetus in 70 singleton pregnancies complicated by preeclampsia and in an additional 70 healthy, normotensive singleton pregnancies. Patients and Methods: After receiving approval from the research and ethical council, this case-control study was carried out at El Hussein University Hospital between November 2022 and December 2023.140 pregnant women having singleton pregnancies were included in this investigation and divided into two categories. The control group consisted of 70 healthy, normotensive singleton pregnancies that went on to deliver a healthy term baby. Pregnant women with singletons exacerbated by preeclampsia (n = 70; one case against one healthy control) made up the study group). Results: We recommend that an additional study be done on this biochemical marker since it has a strong correlation with preeclampsia and elevated levels of urocortin in both the mother and the fetus in preeclamptic instances. Conclusion: Preeclampsia cases have higher plasma urocortin levels in the mother and fetus than in the control group. Additionally, preeclampsia patients have a considerable impact on the middle cerebral artery and uterine artery Doppler indices. | ||||
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