Relationship of Neutrophil to Lymphocyte Ratio (NLR) With Bone Markers and Vascular Changes in Chronic Kidney Disease Patients
Saad, A., Hamed, H., Mosa, M., Khaled, A. (2644). Relationship of Neutrophil to Lymphocyte Ratio (NLR) With Bone Markers and Vascular Changes in Chronic Kidney Disease Patients. EKB Journal Management System, 2023(1), -. doi: 10.58675/2682-339X.1901
Ahmed Alaa Eldin Ahmed M. Saad; Hani Ismail Hamed; Mohamed Farok Ibrahim Mosa; Ahmed Khaled Mohamed Khaled. "Relationship of Neutrophil to Lymphocyte Ratio (NLR) With Bone Markers and Vascular Changes in Chronic Kidney Disease Patients". EKB Journal Management System, 2023, 1, 2644, -. doi: 10.58675/2682-339X.1901
Saad, A., Hamed, H., Mosa, M., Khaled, A. (2644). 'Relationship of Neutrophil to Lymphocyte Ratio (NLR) With Bone Markers and Vascular Changes in Chronic Kidney Disease Patients', EKB Journal Management System, 2023(1), pp. -. doi: 10.58675/2682-339X.1901
Saad, A., Hamed, H., Mosa, M., Khaled, A. Relationship of Neutrophil to Lymphocyte Ratio (NLR) With Bone Markers and Vascular Changes in Chronic Kidney Disease Patients. EKB Journal Management System, 2644; 2023(1): -. doi: 10.58675/2682-339X.1901

Relationship of Neutrophil to Lymphocyte Ratio (NLR) With Bone Markers and Vascular Changes in Chronic Kidney Disease Patients

Al-Azhar International Medical Journal
Volume 2023, Issue 1, January 2023  XML
DOI: 10.58675/2682-339X.1901
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Authors
Ahmed Alaa Eldin Ahmed M. Saad1; Hani Ismail Hamed1; Mohamed Farok Ibrahim Mosa2; Ahmed Khaled Mohamed Khaled3
1Department of Internal Medicine and Nephrology, Faculty of Medicine for boys, Al-Azhar University, Cairo, Egypt
2Department of Clinical Pathology, Faculty of Medicine for boys, Al-Azhar University, Cairo, Egypt
3M.B.B.CH. – Al-Azhar University, Resident of Internal Medicine
Abstract
Background: The neutrophil/lymphocyte ratio (NLR), which increases during inflammation and may be linked to a worse prognosis in CKD, has been the subject of several recent research. Aim and objectives: The objective of the current study was to investigate how individuals with chronic renal disease's neutrophil lymphocyte ratio (NLR) correlated with bone markers and vascular alterations. Patients and methods: This was a prospective case control study which done at Nephrology Department, Ahmed Maher Teaching Hospital, Cairo, Egypt. The study was conducted over a one-year duration, from October 2021 till October 2022. Results: Serum vitamin D showed a significant decline in patients with CKD compared to controls, as it had mean values of 30.34, 20.43, and 20.56 ng/ml in the study groups respectively (p < 0.001). On the other hand, serum PTH had increased levels in CKD groups compared to controls, as it had median values of 40, 101.8, and 391.5 pg/ml in the three study groups respectively. Conclusion: End stage renal disease is associated with a significant increased carotid IMT, reflecting atherosclerotic burden in such patients. CKD is not associated with significant changes in NLR. NLR is not significantly correlated with either bone or vascular changes in CKD patients. Therefore, it should not be used to monitor these changes in the CKD setting.
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