Morphological and Functional Evaluation of the Optic Nerve in Patients Recently Diagnosed as Idiopathic Intracranial Hypertension
Hamed, A., Amin, A., Mahmoud, M. (2645). Morphological and Functional Evaluation of the Optic Nerve in Patients Recently Diagnosed as Idiopathic Intracranial Hypertension. EKB Journal Management System, 2024(1), -. doi: 10.58675/2682-339X.2245
Abdullah Hussein Hamed; Ahmed Mahmoud Ahmed Amin; Mostafa Mahmoud Abbouda Mahmoud. "Morphological and Functional Evaluation of the Optic Nerve in Patients Recently Diagnosed as Idiopathic Intracranial Hypertension". EKB Journal Management System, 2024, 1, 2645, -. doi: 10.58675/2682-339X.2245
Hamed, A., Amin, A., Mahmoud, M. (2645). 'Morphological and Functional Evaluation of the Optic Nerve in Patients Recently Diagnosed as Idiopathic Intracranial Hypertension', EKB Journal Management System, 2024(1), pp. -. doi: 10.58675/2682-339X.2245
Hamed, A., Amin, A., Mahmoud, M. Morphological and Functional Evaluation of the Optic Nerve in Patients Recently Diagnosed as Idiopathic Intracranial Hypertension. EKB Journal Management System, 2645; 2024(1): -. doi: 10.58675/2682-339X.2245

Morphological and Functional Evaluation of the Optic Nerve in Patients Recently Diagnosed as Idiopathic Intracranial Hypertension

Al-Azhar International Medical Journal
Volume 2024, Issue 1, January 2024  XML
DOI: 10.58675/2682-339X.2245
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Authors
Abdullah Hussein Hamed1; Ahmed Mahmoud Ahmed Amin2; Mostafa Mahmoud Abbouda Mahmoud3
1Professor of Ophthalmology Faculty of Medicine - Al-Azhar University
2Assistant professor of Ophthalmology Faculty of Medicine - Al-Azhar University
3M.B.B.Ch Faculty of Medicine, Al-Azhar University
Abstract
Background: Increased intracranial pressure is hallmark of idiopathic intracranial hypertension, known as pseudotumor cerebri. This clinical phenomenon typically affects young, obese women of childbearing age. Aim: The goal of the research had been to determine whether optical coherence tomography (OCT) of the peripapillary nerve fiber layer and visual evoked potential (VEP) could act as a noninvasive surrogate measure of intracranial pressure (ICP) in recently diagnosed idiopathic intracranial hypertension (IIH) or not. Methods: Cross-sectional research was conducted in outpatient clinics of AL-Azhar University Hospital. Twenty studied cases participated in the trial. Results: The mean lumbar puncture pressure in all studied cases had been 38.8 ± 13.3 Cm H2O with a minimum pressure of 26 Cm H2O and a maximum pressure of 75 Cm H2O. As regards retinal nerve fiber layer thickness (RNFLT), the mean RNFLT in all studied cases had been 215.4 ± 65.4 micrometers with minimum RNFLT of 121 micrometers & maximum RNFLT of 340 micrometers. As regards disc area, the mean disc area in all studied cases had been 4.4 ± 1.8 mm² with minimum disc area of 2.18 mm² and maximum disc area of 9.5 mm². Conclusion: As it may aid in identifying modest disc swelling, OCT imaging is more sensitive than clinical findings and may be used as a non-invasive quantitative approach in place of opening pressure but VEP has no role in studied cases recently diagnosed as idiopathic intracranial hypertension.
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