Efficacy of Day 3 versus Day 5 Embryo Transfer in Poor Ovarian Response Infertile Women Undergoing Intracytoplasmic Sperm Injection (ICSI)
Hawas, M., Abou El- Naga, A., Mesbah, Y., Bosilah, A. (2645). Efficacy of Day 3 versus Day 5 Embryo Transfer in Poor Ovarian Response Infertile Women Undergoing Intracytoplasmic Sperm Injection (ICSI). EKB Journal Management System, 2024(10), -. doi: 10.58675/2682-339X.2731
Mohamed Hawas; Amoura Abou El- Naga; Yasser Mesbah; Al Mandouh Bosilah. "Efficacy of Day 3 versus Day 5 Embryo Transfer in Poor Ovarian Response Infertile Women Undergoing Intracytoplasmic Sperm Injection (ICSI)". EKB Journal Management System, 2024, 10, 2645, -. doi: 10.58675/2682-339X.2731
Hawas, M., Abou El- Naga, A., Mesbah, Y., Bosilah, A. (2645). 'Efficacy of Day 3 versus Day 5 Embryo Transfer in Poor Ovarian Response Infertile Women Undergoing Intracytoplasmic Sperm Injection (ICSI)', EKB Journal Management System, 2024(10), pp. -. doi: 10.58675/2682-339X.2731
Hawas, M., Abou El- Naga, A., Mesbah, Y., Bosilah, A. Efficacy of Day 3 versus Day 5 Embryo Transfer in Poor Ovarian Response Infertile Women Undergoing Intracytoplasmic Sperm Injection (ICSI). EKB Journal Management System, 2645; 2024(10): -. doi: 10.58675/2682-339X.2731

Efficacy of Day 3 versus Day 5 Embryo Transfer in Poor Ovarian Response Infertile Women Undergoing Intracytoplasmic Sperm Injection (ICSI)

Al-Azhar International Medical Journal
Volume 2024, Issue 10, October 2024
DOI: 10.58675/2682-339X.2731
Authors
Mohamed Hawas1; Amoura Abou El- Naga1; Yasser Mesbah2; Al Mandouh Bosilah3
1Zoology, Faculty of Science, Mansoura University, Mansoura, Egypt
2Obstetrics and Gynecology, Faculty of Medicine, Mansoura University, Mansoura, Egypt
3Obstetrics and Gynecology, Faculty of Medicine , Damietta University, Damietta, Egypt
Abstract
Background: Poor ovarian response (POR) is a significant treatment challenge faced by women undergoing Assisted Reproductive Technology (ART). Few interventions have specifically addressed embryo transfer (ET) techniques for POR. Aim and objectives: To find out if transferring embryos on day three and day five yields different results for women with POR. Patients and methods: This prospective, randomized controlled trial involved 120 patients with POR who received ICSI between March 2022 and February 2024, aged 35 years or older. Two groups participated: Group 1 comprised 60 women who had fresh or frozen embryo transfers on day 3, and Group 2 comprised 60 women who had the same procedures done on day 5. Results: The study groups did not differ significantly with respect to age, anti-Müllerian hormone (AMH) levels, antral follicle count, and the number of oocytes retrieved. There was no statistically significant difference (p = 0.69) between the groups in terms of pregnancy rate; however, the day 5 (blastocyst stage) group had a higher rate compared to the day 3 (cleavage stage) group (30% vs. 26.7%). Conclusion: Patients with POR may see some advantages with embryo transfers performed on day five rather than day 3, and frozen embryo transfer appears advantageous over fresh transfer. Three high-quality embryos on day 2 of fertilization are required for these results
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