Prevalence of Chronic Endometritis in Unexplained Implantation Failure
Kamel, H., El-Shershaby, S., Moussa, A., Youssof, I., Mahmoud, M. (2644). Prevalence of Chronic Endometritis in Unexplained Implantation Failure. EKB Journal Management System, 2023(1), -. doi: 10.58675/2682-339X.1673
Hossamuddin Hussein Kamel; Shokry Abdul-Azeem El-Awady El-Shershaby; Asem Anwar Abdou Moussa; Ibrahim Hassan Mohammad Youssof; Mohammad El-Sayed El-Saadany Mahmoud. "Prevalence of Chronic Endometritis in Unexplained Implantation Failure". EKB Journal Management System, 2023, 1, 2644, -. doi: 10.58675/2682-339X.1673
Kamel, H., El-Shershaby, S., Moussa, A., Youssof, I., Mahmoud, M. (2644). 'Prevalence of Chronic Endometritis in Unexplained Implantation Failure', EKB Journal Management System, 2023(1), pp. -. doi: 10.58675/2682-339X.1673
Kamel, H., El-Shershaby, S., Moussa, A., Youssof, I., Mahmoud, M. Prevalence of Chronic Endometritis in Unexplained Implantation Failure. EKB Journal Management System, 2644; 2023(1): -. doi: 10.58675/2682-339X.1673

Prevalence of Chronic Endometritis in Unexplained Implantation Failure

Al-Azhar International Medical Journal
Volume 2023, Issue 1, January 2023  XML
DOI: 10.58675/2682-339X.1673
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Authors
Hossamuddin Hussein Kamel1; Shokry Abdul-Azeem El-Awady El-Shershaby2; Asem Anwar Abdou Moussa3; Ibrahim Hassan Mohammad Youssof4; Mohammad El-Sayed El-Saadany Mahmoud3
11Department of Obstetrics & Gynecology, Faculty of Medicine - Al-Azhar University, Egypt
2Department of Obstetrics & Gynecology, International Islamic Center for Population Studies and Research, Al-Azhar University, Egypt
3Department of Obstetrics & Gynecology, Faculty of Medicine - Al-Azhar University, Egypt
4Department of Pathology, Faculty of Medicine - Al-Azhar University, Egypt
Abstract
Background: The actual load of chronic endometritis (CE) in the general population as well as implantation failure is still ill-defined, Aim of the study: was to assess incidence of CE at hysteroscopy and histology, in a cases with implantation failure at ICSI. Patients and methods: The International Islamic Center for Population Studies and Research at Al Azhar University performed this prospective observational cross-sectional research from 2017 to 2022.The study was conducted on 150 women with one unexplained implantation failure or more at ICSI. Results: Histopathological examination confirmed the diagnosis of CE in 55/66 cases suspected to have CE by hysteroscopy (True Positive), while 11 cases were found to be free from CE (False Positive). On the other hand, histopathological examination confirmed absence of CE in 82/84 negative cases by hysteroscopy (True Negative), while only two cases were found to have CE (False Negative). In our study, hysteroscopy is trustworthy CE diagnostic method for CE in unexplained implantation failure with sensitivity, specificity, accuracy, PPV and NPV as 96.5%, 88.17%, 91.3%, 83.3% and, 97.6% respectively. Conclusion: According to this research, hysteroscopy is a useful diagnostic tool in women with unexplained implantation failure as regard CE diagnosis. However, endometrial samples should be obtained during hysteroscopy to increase the diagnostic accuracy.
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