Effects of Vitamin D on Growth Inhibition of Head and Neck Squamous Cell Carcinoma. (In vitro study) | ||
| Al-Azhar Journal of Dentistry | ||
| Volume 4, Issue 4, October 2017, Pages 381-384 PDF (309.49 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/adjg.2017.5285 | ||
| Author | ||
| Heba Hussein | ||
| Oral Medicine, Diagnosis, and Periodontology Department, Faculty of Dentistry, Cairo University | ||
| Abstract | ||
| Objective: To assess the anti-cancer capacity of vitamin D in head and neck squamous cell carcinoma cell line. Materials and Methods: vitamin D cytotoxic effect and cell apoptosis effect were evaluated using Prestoblue cell viability assay and Flow Cytometry. Results: Vitamin D was found to inhibit the cell growth in a dose-dependent manner in head and neck squamous cell carcinoma JHU-29 cell line at three days’ treatment. However, it was not found to cause significant apoptosis at one day treatment. Conclusion: vitamin D inhibits the growth of head and neck squamous cell carcinoma in a dose-dependent manner. | ||
| Keywords | ||
| Head and Neck Squamous Cell; carcinoma; Vitamin D; apoptosis | ||
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