Preparation, Characterization of Two Modified Irradiated Pulp Capping Materials and Evaluation of Anti-Bacterial Activity and Compressive Strength | ||||
| Al-Azhar Journal of Dentistry | ||||
| Volume 2024, Issue 1, January 2024 | ||||
| DOI: 10.58675/2974-4164.1632 | ||||
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| Authors | ||||
| Salma Osama Hamza1; Inas T. Motawea2; Nabila Ahmed Maziad3; Maha Ibrahim Abdelfattah4 | ||||
| 1Assistant lecturer of Dental Biomaterials, Faculty of Dental Medicine for Girls, Al Azhar University, Cairo,Egypt | ||||
| 2Professor of Dental Biomaterials, Dean of the Faculty of Dental Medicine for Girls, Al Azhar University, Cairo, Egypt | ||||
| 3Professor of Radiation Chemistry, National Center for Radiation Research and Technology, Atomic Energy Authority, Cairo, Egypt | ||||
| 4Assistant professor, Department of Oro-Dental Genetics, Medical Research Center of Excellency, National Research Centre, Cairo, Egypt | ||||
| Abstract | ||||
| Purpose: The present study aimed to prepare and characterize irradiated Cross linked Chitosan/Calcium Hydroxide/Urbical copolymer and Propolis powder as modified pulp capping material. Evaluation of the antibacterial activity, compressive strength also had been studied. Materials and Methods: The cross linked Chitosan/Calcium Hydroxide copolymer was prepared by mixing 5ml of Calcium Hydroxide (1%) and 6ml of Chitosan1% (1gm of chitosan was wetted with3.5ml lactic acid for 48 hours which improves the solubility of chitosan in water), then 100 ml distilled water was added, and 2.5ml of HEMA under 25kgy irradiation dose and the resultant was mixed with Urbical (0.03gm base & 0.03gm catalyst).Propolis powder (irradiated and non-irradiated) was mixed with Calcium Hydroxide powder in a ratio of 1:1.5. Propolis was irradiated with 20kgy. Characterization of the structure of the prepared samples was done using FTIR spectroscopy. Compressive strength and antibacterial activity were then studied. Results: Regarding the compressive strength, the significantly highest compressive strength mean value was recorded in Calcium hydroxide group, followed by Non irradiated Propolis /Calcium hydroxide group, however, the cross linked Chitosan/Calcium Hydroxide copolymer recorded the lowest mean value. Regarding antibacterial activity, results revealed that the highest antibacterial activity against streptococcus mutans and Escherichia coli was recorded in cross linked Chitosan-Calcium hydroxide/Urbical copolymer group. However, the antibacterial activity against staphylococcus aureus showed no statistically significance difference between tested groups (p=0.734). Conclusion: Gamma radiation aided in the enhancement of antibacterial activity of the tested two modified irradiated pulp capping materials yet negatively affected their compressive strength. | ||||
| Keywords | ||||
| Irradiation Cross linking; Compressive strength; Chitosan | ||||
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