Evaluation of Glutathione Levels in Gingival Cervical Fluid in Periodontitis from Stage 1 – Stage 4 among Type 2 Diabetic Patients | ||
| Al-Azhar Journal of Dentistry | ||
| Volume 10, Issue 1, January 2023, Pages 159-164 PDF (741.78 K) | ||
| Document Type: Original Article | ||
| DOI: 10.58675/2974-4164.1484 | ||
| Authors | ||
| Maha Elsayed* 1; Mai Attia2; Zienab Farid3 | ||
| 1Dentist at General Authority for Health Insurance B.D.S (2013) MUST University, Egypt. | ||
| 2Professor of Oral Medicine, Periodontology, Oral Diagnosis and Radiology Faculty of Dental Medicine for Girls, Al-Azhar University, Faculty of Oral and Dental Medicine – Misr International University, Cairo, Egypt | ||
| 3Lecturer of Oral Medicine , Periodontology, Oral Diagnosis and Radiology Faculty of Dental Medicine for Girls –Al-Azhar University, Cairo, Egypt | ||
| Abstract | ||
| Purpose: This study aimed to evaluate if glutathione could be used as a diagnostic biomarker in diabetic patients with stage 1, stage 2, stage 3, and stage 4 periodontitis who were receiving non-surgical periodontal therapy. Material and methods: Twentyeight participants were included, who were separated into four groups, each with seven members. Seven diabetic patients with stage 1 periodontitis were assigned to Group 1, seven diabetic patients with stage 2 periodontitis were assigned to Group 2, and seven diabetic patients with stage 3 periodontitis were assigned to Group 3 and Seven diabetic patients with stage 4 periodontitis were assigned to Group 4. Gingival crevicular fluid (GCF) samples were taken from every individual at baseline (before non-surgical periodontal therapy) and one month after non-surgical periodontal therapy was completed. Results: Glutathione levels in the four groups dramatically improved after non-surgical therapy. Conclusion: Glutathione levels should be considered important indicator for prognosis of the periodontal treatment in patients with periodontal disease. | ||
| Keywords | ||
| glutathione; Periodontitis; Diabetic patients | ||
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