Efficacy of Aloe vera in Treatment of Experimentally Induced Oral Lichenoid Reaction | ||||
| Al-Azhar Journal of Dentistry | ||||
| Volume 2022, Issue 10, October 2022 | ||||
| DOI: 10.21608/adjg.2022.124429.1472 | ||||
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| Authors | ||||
Hind Mohmed1; Mai Attia2; Lobna Abd-Alaziz3; Aya Dawaba4; Noura Bakr 5
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| 1Dentist at Al-Azhar Medical Teaching Hospitals. | ||||
| 2Professor of Oral medicine, Periodontology, Diagnosis and Radiology, Faculty of Dental medicine for girls Al-Azhar University, Faculty of Oral and Dental medicine, Misr International University, Cairo, Egypt. | ||||
| 3Lecturer of Oral medicine, Periodontology, Diagnosis and Radiology. Faculty of Dental medicine for girls, Al-Azhar University, Cairo, Egypt. | ||||
| 4Associated professor of pharmaceutics and industrial pharmacy, Faculty of pharmacy for girls, Al-Azhar University, Cairo, Egypt. | ||||
| 5Lecturer of Oral and Dental Biology, Faculty of Dental medicine for girls, Al-Azhar University, Cairo, Egypt. | ||||
| Abstract | ||||
| Purpose: the present study was conducted to compare the efficacy of herbal treatment using Aloe Vera in induced lichenoid reaction versus topical steroids. Materials and methods: thirty-six rats were divided into four groups: 1stgroup control normal group with no induced oral lesions, 2ndgroup (Negative control group) with induced oral lesions but no treatment was used, 3rdgroup (Positive control group) treated with triamcinolone acetonide 0.1% paste, in the 4thgroup(Aloe vera group) treated with topical Aloe vera gel, rats in the 3rd and 4th groups are treated topically for 15 days, samples were taken from the buccal mucosa after the end of the study and sent for histological examination. Results: Histological sections revealed there was a decrease of inflammatory and dysplastic changes of the 3rd and 4th groups in comparison to the 2nd group which received no treatment. Conclusion: Aloe vera might be considered as an accepted alternative treatment option due to their anti-inflammatory, anti-oxidant and anti-neoplastic properties with compared to steroid therapy. | ||||
| Keywords | ||||
| captopril; Aloe vera; Steroid; histological study | ||||
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