Evaluation of Serum Interleukin-10 and Matrix Metalloproteinase-9 Levels as Predictors of Glycemic Alteration in Type 2 Diabetes Mellitus in Patients with Periodontitis | ||||
| Al-Azhar Journal of Dentistry | ||||
| Volume 2020, Issue 10, October 2020 | ||||
| DOI: 10.21608/adjg.2020.14148.1176 | ||||
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| Authors | ||||
| Ayman Elgawish1; Hala Hazzaa2; Eatemad Shoreibah2 | ||||
| 1Assistant lecturer of Oral Medicine, Periodontology, Oral Diagnosis and Dental Radiology, British University in Egypt, Cairo, Egypt | ||||
| 2Professor of Oral Medicine, Periodontology, Oral Diagnosis and Radiology, Faculty of Dental Medicine for Girls, Al-Azhar University, Cairo, Egypt | ||||
| Abstract | ||||
| Purpose: The present study was conducted to evaluate serum interleukin-10 and MMP-9 levels as predictors of glycemic alteration in type 2 Diabetic patients with periodontitis. Subjects and methods: This study was conducted on thirty (30) patients that were divided into two groups: Group 1 fifteen (15) patients with type 2 diabetes and periodontitis; Group 2 fifteen (15) patients with type 2 diabetes and c periodontitis receiving adjunctive treatment Omega-3 and aspirin. Elisa kit was used to evaluate the concentration of serum Mmp-9 and IL-10. Results: There was a statistically significant difference between (Group 1) and (Group 2) in the serum level of Mmp-9 (P-value 0.028) (P-value 0.010) after 3m and 6m as well as the serum level of IL-10(P-value 0.020) (P-value 0.029). Conclusion: Serum IL-10 can be used as predictor of glycemic alteration in type 2 Diabetes Mellitus.Omega-3 can be used as adjunctive treatment in periodontal disease. | ||||
| Keywords | ||||
| Periodontitis; Type 2 Diabetes; MMP-9; IL-10; Omega-3 and aspirin | ||||
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