Evaluation of Controlled Release Simvastatin around Dental Implant in Controlled Type II Diabetic Patient | ||
| Al-Azhar Journal of Dentistry | ||
| Volume 10, Issue 2, April 2023, Pages 401-411 PDF (654.32 K) | ||
| Document Type: Original Article | ||
| DOI: 10.58675/2974-4164.1541 | ||
| Authors | ||
| Salma Baheir1; Mai Attia2; Aya Dawaba3 | ||
| 1Dentist at Medical Administration Center, Al-Azhar University, Cairo, Egypt | ||
| 2Professor of Oral Medicine, Periodontology, Oral Diagnosis and Radiology, Faculty of Dental Medicine for Girls Al-Azhar University & Faculty of Oral and Dental Medicine, Misr International University, Cairo, Egypt | ||
| 3Associate Professor of Pharmaceutics, Faculty of Pharmacy Al-Azhar University, Cairo, Egypt | ||
| Abstract | ||
| Purpose: The goal of this study was to evaluate the clinical effect of topically controlled release simvastatin with dental implant in type II diabetic patients. Materials and Methods: Sixteen diabetic type II patients with missing teeth were selected according to inclusion and exclusion criteria. Patients were divided randomly into two groups using flip coin method. Group I (test group): 8 patients underwent implant placement for missed tooth with controlled released simvastatin around the implant. Group II (control Group): 8 patients underwent implant placement for missed tooth without controlled released simvastatin around the implant. All patients were followed up clinically and radio-graphically for 6 months postoperatively after implant placement. Results: The use of Simvastatin controlled release gel with delayed dental implants decrease postoperative pain and swelling Conclusion: This research showed that the drug delivery system of controlled release simvastatin improve the repair and healing of bone and soft tissue around dental implant in diabetic type II patients | ||
| Keywords | ||
| dental implant; Diabetes type II; Simvastatin | ||
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