Bacterial Coinfections and Antibiogram profiles among ICU COVID-19 patients
Elsharkawy, M., Eid, A., ATTIA, N., Fouda, A. (2644). Bacterial Coinfections and Antibiogram profiles among ICU COVID-19 patients. EKB Journal Management System, 2023(1), -. doi: 10.58675/2636-3305.1656
Mohamed M. Elsharkawy; Ahmed M. Eid; Nancy M. ATTIA; Amr Fouda. "Bacterial Coinfections and Antibiogram profiles among ICU COVID-19 patients". EKB Journal Management System, 2023, 1, 2644, -. doi: 10.58675/2636-3305.1656
Elsharkawy, M., Eid, A., ATTIA, N., Fouda, A. (2644). 'Bacterial Coinfections and Antibiogram profiles among ICU COVID-19 patients', EKB Journal Management System, 2023(1), pp. -. doi: 10.58675/2636-3305.1656
Elsharkawy, M., Eid, A., ATTIA, N., Fouda, A. Bacterial Coinfections and Antibiogram profiles among ICU COVID-19 patients. EKB Journal Management System, 2644; 2023(1): -. doi: 10.58675/2636-3305.1656

Bacterial Coinfections and Antibiogram profiles among ICU COVID-19 patients

Al-Azhar Bulletin of Science
Volume 2023, Issue 1, January 2023  XML
DOI: 10.58675/2636-3305.1656
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Authors
Mohamed M. Elsharkawy1; Ahmed M. Eid1; Nancy M. ATTIA2; Amr Fouda1
1Department of Botany and Microbiology, Faculty of Science, Al-Azhar University, Cairo, Egypt
2Department of Microbiology, Medical Research Institute, Alexandria University, Alexandria, Egypt
Abstract
The fact that patients with a viral respiratory infection are more likely to develop a bacterial infection and the recently reported prevalence of bacterial co-infection among COVID-19 patients in the ICU and its association with serious disease complications. However, the role of co-bacterial infection still needs a lot of study and research. This study was designed to investigate the frequency and etiology of bacterial infections in patients with COVID-19 admitted to the ICU and exploring their antibiogram sensitivity. We conducted the blind mini-bronchoalveolar lavage (BAL) sampling technique, VITEK 2 compact system for bacterial identification; K. pneumoniae was the most frequently reported pathogen, followed by P. Mirabilis and A. baumannii respectively. Antibiotic susceptibility testing was performed by two methods; according to CLSI guidelines using disc diffusion assay with 19 antibiotics and by VITEK 2-AST. The results proved the extensive multidrug resistant of co-bacterial pathogens to tested beta-lactams, carbapenems, aminoglycosides, quinolones, tetracycline, rifamycin and sulfonamide, however, P. Mirabilis showed considerable susceptibility to amikacin, while colistin was highly active against A. baumannii, in addition to sensitivity of K. pneumoniae for azteronam and colistin. This study may be useful in controlling nosocomial infections and the spread of antibiotic resistance and strict supervision of antibiotic stewardship programs.
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