Microscopic changes of nasal mucosa in atrophic rhinitis (Ozena) before and after nasal closing operation. | ||||
| Benha Medical Journal | ||||
| Articles in Press, Accepted Manuscript, Available Online from 09 July 2025 PDF (465.42 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/bmfj.2025.369868.2349 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Ahmed M El-Hewity  ; Hany A Riad
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| Department of Otorhinolaryngology, head and neck surgery, Benha University, Egypt. | ||||
| Abstract | ||||
| Background: Assess the return of nasal mucosa to the respiratory type epithelium after nasal closing operation to assess its impact on nasal anatomy and physiology. Patients and methods: This prospective randomized study was carried out in the Otorhinolaryngology and Histopathology Department of Benha University Hospital over a three-year period, from 2019 to 2022. The study cohort consisted of thirty-six cases of primary Atrophic Rhinitis, following approval from the research ethics committee, identified by code number RC1-1-2025, and after obtaining informed consent from the patients. Results: Total number of 36 patients , with male percentage 10 (27.7%) and female percentage 26 (72.3%)Rural to urban ratio 3.2 :1 and the main histopathological pictures in patients preoperatively, postoperatively and 6 months postoperatively seen in the study are shown in table 4. Conclusion: After the nasal obstruction of patients with atrophic rhinitis, the affected pseudostratified columnar epithelium of the atrophic nose advances to metaplasia. Transforming into stratified squamous epithelium with or without slight keratinization. Submucosal fibrosis escalates alongside glandular structures in addition to vasodilation. These alterations may account for the relief of symptoms like crusting, infections, and unpleasant smells. Nonetheless, even with symptom relief, the nasal mucosa does not revert to its normal state. | ||||
| Keywords | ||||
| Atrophic rhinitis; respiratory epithelium; ozena | ||||
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