Lactoferrin Alone Vs Iron Alone Vs Lactoferrin Plus Iron for Treatment of Iron Deficiency Anemia During The 3rd Trimester of Pregnancy (Randomized Controlled Trial) | ||||
| Evidence Based Women's Health Journal | ||||
| Volume 15, Issue 15, January 2025, Page 1-7 PDF (436.07 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ebwhj.2025.348714.1412 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Ahmad Ali M. Nasr; Medhat kamel fathy; Rehab Ahmad Amine Ahmad 
| ||||
| Department of Obstetrics and Gynecology, Faculty of Medicine, Al-Azhar University, Assuit, Egypt. | ||||
| Abstract | ||||
| Background and Aim: Iron deficiency (ID) is a condition that is associated with an elevated risk of preterm delivery, fetal growth retardation, low birth weight, and inferior newborn health. This condition is frequently caused by elevated needs for iron throughout gestation. The purpose of the research was to compare the effectiveness of lactoferrin alone, iron alone, and lactoferrin with iron for the management of iron deficiency anemia throughout the third trimester of gestation. Patients and Methods: This prospective randomized controlled trial has been performed on 300 patients at the Obstetrics and Gynecology Department, Al-Azhar University Hospital, Assiut from 1st of June 2023 to 1st of June 2024. Patients divided into 3 groups; Group A: 100 anemic pregnant females have been managed with lactoferrin only twice daily for 4 weeks. Group B: 100 anemic pregnant females have been managed with amino a` chelated iron only twice daily for 4 weeks as control group and Group C: 100 anemic pregnant women were treated with lactoferrin with amino a` chelated iron once daily for 4 weeks. Results: According to complications, there was statistically significant increase in group 2 than other groups regarding abdominal pain, constipation, nausea, vomiting and dark stool. According to fetal and neonatal outcomes, there were statistically insignificant variances between the three studied groups. Conclusion: The iron group showed increased poor treatment compliance with abdominal pain, constipation, nausea, vomiting, and dark stool, with an increase in combined lactoferrin levels compared to other groups. | ||||
| Keywords | ||||
| ID; iron; preterm delivery; lctoferrin with | ||||
|
Statistics Article View: 46 PDF Download: 20 |
||||
