Comparative Study of Induction of Labour at term by Misoprostol Vaginal Insert versus Dinoprostone Vaginal Insert

Abdel-Bagy, Aly; Mekky, Mohamed Hamed; essam, reham; Farouk, hany ahmed; Salah, Mohamed; Anan, Mohamed

doi:10.21608/aumj.2025.332946.1157

	Comparative Study of Induction of Labour at term by Misoprostol Vaginal Insert versus Dinoprostone Vaginal Insert
Aswan University Medical Journal
Article 13, Volume 5, Issue 3, September 2025, Page 118-125 PDF (328.02 K)
Document Type: Original Article
DOI: 10.21608/aumj.2025.332946.1157
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Authors
Aly Abdel-Bagy¹; Mohamed Hamed Mekky ¹; reham essam²; hany ahmed Farouk¹; Mohamed Salah¹; Mohamed Anan¹
¹Department of obstetrics and gynaecology, faculty of medicine, Aswan university
²Department of Obstetrics & gynecology Faculty of Medicine, Aswan University
Abstract
Background: Ineffective labor and excessive uterine activity, which can result in fetal hypoxia and raise the danger of induction, are the primary issues with inducing labor. Aim: To compare the efficacy, safety of a dose of 25µg vaginal misoprostol versus 3mg dinoprostone vaginal insertion in induction of labor at term. Patients and methods: This was a randomized controlled, single blind study conducted on 50 patients who were candidates for labor induction at term. The low-risk patients with unfavorable cervices before induction of labor were targeted at Obstetrics & Gynaecolog department, Aswan University Hospital, Egypt from march 2023 to september 2023. Results: Regarding delivery outcomes in two groups, In Group A, 20 cases of successful vaginal delivery were reported, with 5 cases requiring CS. Two cases were due to induction failure and three to severe fetal bradycardia. The mean induction time was 613 minutes. In Group B, 22 cases had successful vaginal delivery, with 3 cases requiring CS. The mean induction time was 327 minutes. there was no significant difference between two groups regarding Side effects and delivery complications p>0.05. Regarding fetal complications among the study subjects, in Group A and Group B the mean APGAR score was 8 while 2 neonates in each group required early NICU admission. Conclusion: According to the results of our study, Dinoprostone gives less time and can be used safely in induction of labour.
Keywords
Induction of Labour; Misoprostol Vaginal Insert; Dinoprostone Vaginal Insert; Outcome


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