Potential Impact of Blood Pressure Variability on Right-Ventricular Remodeling in Pregnant Women with Pre-Eclampsia or Gestational Hypertension
Mohamed Soliman, A., Elsayed Abdellatif, M., Mohammed, H., Hanafy Mahmoud, A. (2025). Potential Impact of Blood Pressure Variability on Right-Ventricular Remodeling in Pregnant Women with Pre-Eclampsia or Gestational Hypertension. EKB Journal Management System, 5(3), 172-186. doi: 10.21608/aumj.2025.374579.1225
Aml Mohamed Soliman; Mahmoud Elsayed Abdellatif; Hossam El-Dein Mohammed; Amr Hanafy Mahmoud. "Potential Impact of Blood Pressure Variability on Right-Ventricular Remodeling in Pregnant Women with Pre-Eclampsia or Gestational Hypertension". EKB Journal Management System, 5, 3, 2025, 172-186. doi: 10.21608/aumj.2025.374579.1225
Mohamed Soliman, A., Elsayed Abdellatif, M., Mohammed, H., Hanafy Mahmoud, A. (2025). 'Potential Impact of Blood Pressure Variability on Right-Ventricular Remodeling in Pregnant Women with Pre-Eclampsia or Gestational Hypertension', EKB Journal Management System, 5(3), pp. 172-186. doi: 10.21608/aumj.2025.374579.1225
Mohamed Soliman, A., Elsayed Abdellatif, M., Mohammed, H., Hanafy Mahmoud, A. Potential Impact of Blood Pressure Variability on Right-Ventricular Remodeling in Pregnant Women with Pre-Eclampsia or Gestational Hypertension. EKB Journal Management System, 2025; 5(3): 172-186. doi: 10.21608/aumj.2025.374579.1225

Potential Impact of Blood Pressure Variability on Right-Ventricular Remodeling in Pregnant Women with Pre-Eclampsia or Gestational Hypertension

Aswan University Medical Journal
Article 18, Volume 5, Issue 3, September 2025, Pages 172-186    PDF (1.06 M)
Document Type: Original Article
DOI: 10.21608/aumj.2025.374579.1225
Authors
Aml Mohamed Soliman; Mahmoud Elsayed Abdellatif* ; Hossam El-Dein Mohammed; Amr Hanafy Mahmoud
Department of Cardiology, Faculty of Medicine, Aswan University,
Abstract
Background: Hypertensive disorders of pregnancy complicate up to 10% of pregnancies and represent a significant cause of maternal and perinatal morbidity and mortality. The aim of this study was to evaluate blood pressure (BP) variability and right ventricular (RV) remodeling in women with gestational HTN (GH) and PE, as well as their association. Methods: This observational comparative study included 40 female patients with pregnancy-related hypertensive disorders (Group A) and 20 healthy pregnant women as a control group (Group B) at Aswan University hospital. Results: At three-month follow-up, systolic/diastolic BP, RV dimensions, and RV strain remained significantly higher in the cases group, whereas SD of systolic BP and S' were lower (P<0.05). RV structure and function were similar between preeclampsia and gestational hypertension groups, except for higher RAVI, global RV, and free wall RV strain in preeclampsia (P<0.05). Maternal and fetal complications showed no significant difference between groups.
Conclusions: BP variability significantly impacts RV remodeling in pregnant women with GH and PE. Despite similar maternal and fetal complication rates between groups, the persistence of elevated BP and RV abnormalities postpartum underscores the need for ongoing cardiovascular monitoring and management.
Keywords
Blood Pressure; Right Ventricular Remodeling; Pregnancy; Pre-Eclampsia; Gestational Hypertension
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