Antibacterial Effect of Various Antibiotics on Enterococci: A Comparative Study | ||
| Bulletin of Faculty of Science, Zagazig University | ||
| Article 1, Volume 2025, Issue 4, October 2025, Pages 1-10 PDF (874.72 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/bfszu.2025.354672.1471 | ||
| Author | ||
| Nabawy Mostafa Elnabawy* | ||
| Chemistry and Microbiology, Science, Zagazig, Egypt | ||
| Abstract | ||
| Enterococci, a genus of Gram-positive bacteria, have gained recognition as significant nosocomial pathogens due to their remarkable ability to resist many commonly used antibiotics and their propensity to acquire resistance genes. Theses pathogens pose a substantial challenge in healthcare settings, particularly among immunocompromised patients, as they are associated with arange infections, including urinary tract infections, endocarditis,and bacteremia . This study aims to assess the antibacterial efficiency of widely used antibiotics against Enterococcus species, focusing on their resistance patterns and susceptibility profiles. A specific emphasis is placed on Vancomycin -resistant enterococci (VRE),which have emerged as a critical concern due to limited therapeutic options.The findings reveal high levels of resistance to first-line antibiotics,underscoring the role of intrinsic and acquired resistance mechanisms.Despite this, certain antibiotics demonstrate promising efficacy, offering potential therapeutic avenues for managing enterococcal infections. The results emphasize the urgent need for robust antibiotic stewardship programs to curb the spread of resistant strains and preserve the efficacy of existing antibiotics. Additionally,continuous surveillance of resistance patterns is crucial to inform clinical decisions and guide empirical therapy. These efforts are vital in addressing the growing threat posed by enterococcal infections in healthcare settings and ensuringeffective treatment options remain available. | ||
| Keywords | ||
| Keywords: Enterococci; antibiotic resistance; vancomycin; susceptibility; nosocomial infections | ||
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