Acne Vulgaris: Pathogenesis, Clinical Manifestations and Therapeutic Lines
Zahran, E., Ibrahim, A., Mohammed, L., Ibrahim, S. (2025). Acne Vulgaris: Pathogenesis, Clinical Manifestations and Therapeutic Lines. EKB Journal Management System, 10(1), 47-52. doi: 10.21608/bjas.2025.357410.1580
Esraa Mahmoud Zahran; Adel Ali Ibrahim; Lina Abdelhady Mohammed; Samah Ibrahim. "Acne Vulgaris: Pathogenesis, Clinical Manifestations and Therapeutic Lines". EKB Journal Management System, 10, 1, 2025, 47-52. doi: 10.21608/bjas.2025.357410.1580
Zahran, E., Ibrahim, A., Mohammed, L., Ibrahim, S. (2025). 'Acne Vulgaris: Pathogenesis, Clinical Manifestations and Therapeutic Lines', EKB Journal Management System, 10(1), pp. 47-52. doi: 10.21608/bjas.2025.357410.1580
Zahran, E., Ibrahim, A., Mohammed, L., Ibrahim, S. Acne Vulgaris: Pathogenesis, Clinical Manifestations and Therapeutic Lines. EKB Journal Management System, 2025; 10(1): 47-52. doi: 10.21608/bjas.2025.357410.1580

Acne Vulgaris: Pathogenesis, Clinical Manifestations and Therapeutic Lines

Benha Journal of Applied Sciences
Volume 10, Issue 1, January 2025, Page 47-52  XML PDF (393.33 K)
Document Type: Original Research Papers
DOI: 10.21608/bjas.2025.357410.1580
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Authors
Esraa Mahmoud Zahran email 1; Adel Ali Ibrahim2; Lina Abdelhady Mohammed3; Samah Ibrahim4
1(MB, B.CH), Faculty of Medicine - Alexandria University, Egypt
2Professor of Dermatology, Venereology and Andrology Faculty of Medicine Benha University
3Assistant Professor of Medical Biochemistry Faculty of medicine, Benha University
4Department of Dermatology and Andrology, Faculty of Medicine, Benha University, Benha , Egypt
Abstract
One example of a chronic inflammatory condition is acne vulgaris. Causes of chronic acne include overproduction of sebum, abnormal follicular infundibulum keratinisation, the spread of bacteria, and subsequent inflammation, as well as endocrinological variables like androgens. The pathophysiology of this condition usually starts in the early teen years but may continue far into adulthood. The most common areas to find lesions are on the chest, upper back, neck, and face. Among the many types of acne, you may find those specific to certain situations or occupations, such as neonatal or infantile acne, acne conglobata, acne fulminans, acne mechanica, excoriated acne, chloracne, or acne produced by certain medications, such as anabolic steroids, corticosteroids, lithium, or phenytoin. To lessen the emotional and social toll of the condition, there are a number of helpful medication options, both topically and systemically applied. Oral medications (such as tetracyclines, macrolides, and isotretinoin) and hormonal treatments (such as oral contraceptives and systemic glucocorticoids or GnRH agonists) are the most common methods of treating acne vulgaris, although topical medications (like benzoyl peroxide (BP), topical antibiotics, retinoids, azelaic acid, dapsone, etc.) and oral medications in general are also used frequently.
Keywords
Acne vulgaris; Pathogenesis; Clinical manifestations; Therapeutic lines; Inflammation
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