Antibacterial activity of silver nanoparticles synthesized by Raoultella ornithinolytica from dental root canal infections | ||||
| Microbial Biosystems | ||||
| Article 3, Volume 10, Issue 3, September 2025, Page 6-14 PDF (610.5 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/mb.2025.359969.1254 | ||||
 View on SCiNiTO | ||||
| Author | ||||
Mohammed Waleed Abas Abd Ali 
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| Department of Biology, College of Science, University of Misan, Misan, Iraq. | ||||
| Abstract | ||||
| This study aimed to utilize AgNPs generated by Raoultella ornithinolytica bacteria as antibacterial activity against a Streptococcus gordonii. The production of nanomaterial and their application in biology and medicine exemplify the significant uses of the distinctive structural dimensions and configurations that have propelled nanotechnology's rapid ascent as a discipline of Nano science. Unlike eukaryotic cells, bacterial cells can swiftly create many physiologically active compounds due to their efficient metabolic pathways. This lets bacteria outperform eukaryotic cells. R. ornithinolytica collected from parsons with dental issues to produce silver nanoparticles in an eco-friendly and cost-effective manner. The nanoparticles have been tested against multidrug-resistant Streptococcus gordonii alone and in combination with other antibiotics. These bacteria were identified by morphology, biochemistry, and molecular approaches. The results were shown that several antibiotics, including Optochin OP, Tetracycline TE, Erythromycin E, and Streptomycin S., exhibited a synergistic impact on the suppression of S. gordonii bacteria when combined with silver nanoparticles (AgNPs). Conversely, streptomycin and tetracycline antibiotics exhibited contrasting effects. In summary, S. gordonii isolates were significantly suppressed by R. ornithinolytica (AgNPs); hence, (AgNPs) possess many applications in oral care. This study aimed to deliver a succinct summary of the various dental care applications of AgNPs. The study utilized AgNPs generated by R. ornithinolytica bacterial strains S1, S2, and S7 for individuals with oral issues. The antibacterial activity of (AgNPs) derived from R. ornithinolytican is demonstrated against a S. gordonii strain. | ||||
| Keywords | ||||
| Antagonistic effect; dental diseases; drug resistance; green synthesis; XRD | ||||
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