Serum 25 hydroxy vitamin D level in patients with telogen effluvium | ||||
Egyptian Journal of Medical Research | ||||
Volume 6, Issue 2, April 2025, Page 166-175 PDF (491.04 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/ejmr.2025.322971.1700 | ||||
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Authors | ||||
Hanan Abdelrazik kamel1; Abd El Aziz Ibrahim Eltaweel1; Wessam Adel Elbiomy ![]() | ||||
1Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Beni-Suef University, Egypt | ||||
2Clinical and Chemical Pathology, Faculty of Medicine, Beni-Suef University, Egypt | ||||
Abstract | ||||
In order to better understand Telogen Effluvium (TE) and its relationship to vitamin D status, this study set out to measure vitamin D levels in individuals with the condition. Group A consisted of 45 patients having a diagnosis of TE, whereas Group B consisted of 45 healthy individuals who were age and sex-matched but had no history of TE. The Beni Suef University Hospitals Dermatology and Andrology Department's Outpatient Clinic recruited the patients. Lab tests, a dermatological evaluation, a trichoscopic evaluation, a general physical examination (to identify systemic reasons of hair loss), and a medical history (including age, beginning of disease, duration of sickness, and family history) were all part of each patient's thorough evaluation. With the use of ELISA kits, we were able to measure the concentrations of 25-hydroxyvitamin D in the blood A statistically significant reduction in vitamin D levels was seen in the case group compared to the control group. Furthermore, there was a statistically significant rise in the prevalence of inadequate and insufficient vitamin D levels among the patients in comparison to the control group. There was no proven correlation between age and vitamin D levels. Nevertheless, we found a significantly negative correlation between duration and vitamin D levels in the case group. Vitamin D 25 (OH) levels were significantly lower in those whose families had a history of the disease compared to those whose families did not. | ||||
Keywords | ||||
Vitamin D; telogen effluvium | ||||
References | ||||
1- Ozlu E and Karadag AS. Telogen effluvium. In: Kutlubay Z, Serdaroglu S, editors. Hair and Scalp Disorders. 7th ed. China: InTech 2017; 198–203.
2- Rebora A. Proposing a simpler classification of telogen effluvium. Skin Appendage Disord J 2016; 2(1): 35-8.
3- Dabbour I.R., Jazar A.S. and Azzeh F.S. Vitamin D Status in Patients with Type 2 Diabetes Mellitus in Makkah Region of Saudi Arabia. Pak. J. Nutr. 2016; 203-210.
4- Casey CF, Slawson DC and Lindsey R. Role of vitamin D in metabolism and absorption of minerals. American Family Physician 2010; 81(6): 745-750.
5- Gupta R, Gupta RK, Saheen A, et al. Role of Vitamin D in Children. JIMSA 2014; 27(4): 229-231.
6- Bhat YJ, Latif I, Malik R, Hassan I, Sheikh G and Lone KS. Vitamin D level in alopecia areata. Indian J Dermatol 2017; 62(4): 407-10.
7- Bikle DD. Vitamin D and the skin. J. Bone Miner. Metab. 2010; 28: 117-30.
8- Phillips TG, Slomiany WP, Allison R. Hair loss: common causes and treatment. Am Fam Physician 2017; 96: 371–378.
9- Bozkurt S, Alkan BM, Yıldız F, Gümüş S, Sezer N, Ardıçoğlu Ö, et al. Age, sex, and seasonal variations in the serum vitamin D3 levels in a local Turkish population. Arch Rheumatol 2014; 14-9.
10- Seleit I, Bakry OA, Badr E and Hassan EH. Vitamin D receptor gene polymorphism in chronic telogen effluvium: A case-control study. Clinica, Cosmetic and Investigational Dermatology 2019; 12: 745-750.
11- Aslan N. Evaluation of vitamin D levels in chronic telogen effluvium patients. Turkiye Kliniklerj J Dermatol 2018; 28(2): 51-5.
12- Mohammad NM, Ibrahium RS, Mohammed MH, Galal SA, Maher R. Etiological Role of Ferritin and Vitamin D in Patients with Telogen Effluvium . J Clin Exp Dermatol Res 2017; 8: 431.
13- Gerkowicz A, Chyl-Surdacka K, Krasowska D and Chodorowska G. The role of vitamin D in non-scarring alopecia. Int J Mol Sci 2017; 18: E2653.
14- Karadağ AS, Ertuğrul DT, Tutal E. The role of anemia and vitamin D levels in acute and chronic telogen effluvium. Turk J Med Sci 2011; 41(5): 827-33.
15- Cheung EJ, Sink JR, English JC III. Vitamin and mineral deficiencies in patients with telogen effluvium: a retrospective cross-sectional study. J Drugs Dermatol 2016; 15: 1235–1237.
16- Gürel G, Karadöl M, Çölgeçen E. The role of ferritin and vitamin D levels in telegon effluvium. Turkiye Klinikleri J Dermatol 2017; 27(3): 113-6. | ||||
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