A Comprehensive Review on Novasomes As Lipid-Based Drug Carriers | ||||
| Sinai International Scientific Journal | ||||
| Volume 2, Issue 1, July 2025, Page 21-35 PDF (738.02 K) | ||||
| Document Type: Narrative Review Article | ||||
| DOI: 10.21608/sisj.2025.442481 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Yasmin Ismail mortaga  ; Rana E. Elnady
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| Department of Pharmaceutics, Faculty of Pharmacy, Sinai University, Arish Branch, North Sinai 45511, Egypt | ||||
| Abstract | ||||
| Background: Novasomes (Novs) are a novel lipid-based drug delivery system (LBDDS) for enhanced drug delivery. Those systems are composed of surface active agents (SAA) and free fatty acids (FFA) that self-assemble into spherical bilayer structures to encapsulate a variety of therapeutic drugs. Novs have been extensively studied as drug carriers, including antifungals, antibiotics, anti- inflammatory, and anticancer drugs. They approved better solubility and permeability, greater therapeutic efficacy, and diminished side effects when compared to free drug formulations. Aims of this review: This review provides a thorough outlook, including novasomal constituents, development techniques, advantages and disadvantages, variant characterizations, routes of administration, pharmacological applications, and future prospects in the field of novasomal research. | ||||
| Keywords | ||||
| Novs; lipid-based nanocarrier; non-ionic surfactants; permeability | ||||
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