Recent Biological Activity of Ferulic Acid | ||||
| Sinai International Scientific Journal | ||||
| Volume 2, Issue 1, July 2025, Page 102-114 PDF (437.3 K) | ||||
| Document Type: Narrative Review Article | ||||
| DOI: 10.21608/sisj.2025.442506 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Mohamed H.A. Gadelmawla   1; Hossam H. Nasrallah2
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| 1Histology Department, Faculty of Dentistry, Sinai University, Ismailia, Egypt | ||||
| 2Basic Sciences Department, Faculty of Dentistry, Sinai University, Ismailia, Egypt | ||||
| Abstract | ||||
| A common ingredient in fruits, drinks, and food products is 4- hydroxycinnamic acid, which is the source of ferulic acid (FA). Scientific evidence has shown that it has anti-inflammatory, antioxidant, and antimicrobial properties. Its clinical use, for example, is limited to low bioavailability and is therefore only useful in treating neurological illnesses such as Alzheimer's disease, rapid elimination from the gastrointestinal tract after oral treatment, and inadequate translocation across biological barriers, such as the blood-brain barrier (BBB). Consequently, novel nanotechnological strategies are created to control FA's intracellular transit. This review summarizes twenty years of research on FA's biological properties. | ||||
| Keywords | ||||
| ferulic acid; antioxidants; neuroprotective action; anticancer | ||||
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