Measurement of serum levels of interleukin 17 in acne vulgaris Patients and its relation to severity of the disease | ||
| Egyptian Journal of Medical Research | ||
| Volume 6, Issue 2, April 2025, Pages 197-207 PDF (396.13 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejmr.2024.300692.1634 | ||
| Authors | ||
| Abd El-Aziz Ibrahim Eltaweel1; Marmar Ahmed Ezz* 2; Hoda Ramadan Riad3; Hanan Abdelrazik kamel4 | ||
| 1Dermatology and Andrology Benha University | ||
| 2Dermatology Department October 6 University | ||
| 3Biochemistry Department, Faculty of Medicine, Beni-Suef University, Egypt | ||
| 4Dermatology & Andrology Department, Faculty of Medicine, Beni-Suef University, Egypt | ||
| Abstract | ||
| The purpose of this research was to examine the role of IL-17 in acne vulgaris (AV) patients especially in the development of scarring lesions, the severity of illness, and disease etiology. Fifty patients with AV of varied severity (Group A) were included in this case-control study from the Outpatient Clinic of the Dermatology Department at Beni Suef University Hospitals. Thirty healthy volunteers, matched for age and sex, made up the control group IL-17 serum levels were reviewed using ELIZA among study contributors. The age and sex distributions of the groups under study did not differ significantly. Mild acne accounted for 36% of the patients, moderate for 34%, and severe for 30%. Scarring was seen in 28% of the subjects in the present study. The levels of IL-17 were significantly higher in the case group when compared with the control group. There are still gaps in our understanding of the pathophysiology of this common condition, and this study's results points to interrelationships between IL-17 and AV etiology | ||
| Keywords | ||
| Acne vulgaris; interleukin 17; Severity | ||
| References | ||
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