Interaction of Zinc Nanoparticles with Malathion on Nile Tilapia | ||
| Egyptian Journal of Veterinary Sciences | ||
| Articles in Press, Corrected Proof, Available Online from 22 July 2025 PDF (786.62 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejvs.2025.362035.2655 | ||
| Authors | ||
| Nehal Kahwagy1; Gehad El-Sayed2; Mohamed El-Adl* 3; Nevien Abdelkhalek1 | ||
| 1Veterinary Medicine, Mansoura University | ||
| 2Mansoura University Veterinary Medicine | ||
| 3Biochemistry department, Faculty of Veterinary Medicine, Mansoura University | ||
| Abstract | ||
| Aquaculture has emerged as a crucial approach to sustainably meet the growing global demand for protein. Nile tilapia (Oreochromis niloticus), a prominent freshwater species, is important in aquaculture and culinary applications. This research examined the interaction of zinc oxide nanoparticles and malathion pesticides on Nile tilapia. Nile tilapia received 2 mg/L Zinc oxide nanoparticles and/or 3 mg/L Malathion. After thirty days, serum samples were collected for the determination of hepatic damage markers, hepatic and branchial antioxidant status, and gene expression analysis for immune genes. A significant decrease in the ALT/AST ratio was detected in all treated groups. Zinc oxide nanoparticles improved antioxidant status and decreased lipid peroxidation levels in the malathion-intoxicated group, significantly reducing proinflammatory cytokines. This study highlighted the potential and specificity of zinc oxide nanoparticles in alleviating the toxicity of malathion in Nile tilapia which gave insights into ameliorating the toxicity of pesticides with physiological metal nanoparticles in aquaculture. | ||
| Keywords | ||
| Malathion; Nanoparticles; Tilapia; Zinc oxide | ||
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